Proteins in eukaryotic transcription /

• Άλλοι συγγραφείς: Conaway, Ronald C., Conaway, Joan Weliky
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Amsterdam ; Boston : Elsevier Academic Press, ©2004.
• Σειρά: Advances in protein chemistry ; v. 67.
• Θέματα: Genetic transcription > Regulations.; Eukaryotic cells.; RNA polymerases.; Transcription factors.; Histones.; Transcription génétique > Régulation.; Cellules eucaryotes.; ARN polymérases.; Facteurs de transcription.; SCIENCE > Life Sciences > Biochemistry.; Genetic transcription.; Eiwitten.; Eukaryoten.; Transcriptie (biochemie); RNA-polymerasen.; Mediatoren.; Liganden.; Histonen.; Eukaryotic Cells.; Gene Expression Regulation.; Transcription Factors.; Transcription, Genetic.; DNA-Directed RNA Polymerases.; Electronic books.; Rules.

 Protein Transcription is a key element of cellular and organ regulation. This volume covers structure and function of all major elements associated with transcription. 

 Cover -- Proteins in Eukaryotic Transcription -- Copyright Page -- CONTENTS -- PREFACE -- Chapter 1. Structure and Function of RNA Polymerase II -- I. Perspective -- II. Structure of RNA Polymerase II -- III. Function of RNA Polymerase II -- IV. Comparison with Other Polymerases -- V. Conclusions -- References -- Chapter 2. The Mediator Complex -- I. Summary -- II. Saccharomyces cerevisiae Mediator -- III. Mediator Complexes in Higher Eukaryotes -- IV. Mechanism of Transcriptional Activation -- V. Concluding Remarks -- References -- Chapter 3. Structure and Function of the TFIID Complex -- I. TFIID and Transcription Initiation -- II. TFIID Components and Structure -- III. TFIID Functions -- IV. The Requirement for TFIID In Vivo -- V. Regulation of TFIID -- VI. The TFIID-Chromatin Connection -- VII. Future Questions -- References -- Chapter 4. Tetratricopeptide Repeats of TFC4 and a Limiting Step in the Assembly of the Initiation Factor TFIIIB -- I. Introduction -- II. Brf1-TFIIIC: A Limiting Interaction in Preinitiation Complex Assembly -- III. Brf1-Tfc4 Interactions -- IV. Bdp1-Tfc4 Interactions -- V. Ligand Binding by TPR Arrays in Tfc4 -- VI. Ordered Binding of TFIIIB Subunits to TFIIIC-DNA and Dynamic Interactions with Tfc4 -- VII. Tfc4 and Other Pol III Factors -- VIII. Conclusion -- References -- Chapter 5. Mechanism of RNA Polymerase I Transcription -- I. Introduction -- II. Ribosomal DNA Gene Structure -- III. Species-Specificity of Ribosomal RNA Transcription -- IV. Factors Involved in Ribosomal RNA Transcription -- V. Assembly of an RNA Polymerase I Initiation Complex in Vertebrates -- VI. Factors Required for RNA Polymerase I Transcription in Yeast -- VII. Regulatory Mechanisms -- VIII. Chromatin and RNA Polymerase I Transcription -- IX. Conclusions -- Acknowledgments -- References -- Chapter 6. Functional Properties of ATP-Dependent Chromatin Remodeling Enzymes -- I. Introduction -- II. History of Nucleosome-Remodeling Complexes -- III. Requirements for Nucleosome-Remodeling Enzymes -- IV. Mechanisms of ATP-Dependent Chromatin Remodeling -- V. Initiation of ATP-Dependent Chromatin Remodeling -- VI. Conclusions -- Acknowledgments -- References -- Chapter 7. Histone Acetyltransferase Proteins Contribute to Transcriptional Processes at Multiple Levels -- I. Introduction -- II. HATs and HAT Complexes: New Insights into HAT Regulation and Effects on Transcription -- III. HAT Complexes Functionally Interact with Chromatin- Remodeling Complexes and Influence Transcription -- IV. HAT Proteins Function in Regulating Transcriptional Elongation -- V. The Histone Code: Insights into Epigenetic Regulation of Transcription -- VI. HATs: New Insight into Transcription and DNA Repair -- VII. Conclusion and Perspectives -- Acknowledgments -- References -- Chapter 8. Posttranslational Modifications of Histones by Methylation -- I. Introduction -- II. Lysine Methyltransferases -- III. Arginine Methyltransferases -- IV. Epilogue -- References -- Author Index.