Proteins in eukaryotic transcription /

• Άλλοι συγγραφείς: Conaway, Ronald C., Conaway, Joan Weliky
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Amsterdam ; Boston : Elsevier Academic Press, ©2004.
• Σειρά: Advances in protein chemistry ; v. 67.
• Θέματα: Genetic transcription > Regulations.; Eukaryotic cells.; RNA polymerases.; Transcription factors.; Histones.; Transcription génétique > Régulation.; Cellules eucaryotes.; ARN polymérases.; Facteurs de transcription.; SCIENCE > Life Sciences > Biochemistry.; Genetic transcription.; Eiwitten.; Eukaryoten.; Transcriptie (biochemie); RNA-polymerasen.; Mediatoren.; Liganden.; Histonen.; Eukaryotic Cells.; Gene Expression Regulation.; Transcription Factors.; Transcription, Genetic.; DNA-Directed RNA Polymerases.; Electronic books.; Rules.

Protein Transcription is a key element of cellular and organ regulation. This volume covers structure and function of all major elements associated with transcription.

Πίνακας περιεχομένων:

• Cover
• Proteins in Eukaryotic Transcription
• Copyright Page
• CONTENTS
• PREFACE
• Chapter 1. Structure and Function of RNA Polymerase II
• I. Perspective
• II. Structure of RNA Polymerase II
• III. Function of RNA Polymerase II
• IV. Comparison with Other Polymerases
• V. Conclusions
• References
• Chapter 2. The Mediator Complex
• I. Summary
• II. Saccharomyces cerevisiae Mediator
• III. Mediator Complexes in Higher Eukaryotes
• IV. Mechanism of Transcriptional Activation
• V. Concluding Remarks
• References
• Chapter 3. Structure and Function of the TFIID Complex
• I. TFIID and Transcription Initiation
• II. TFIID Components and Structure
• III. TFIID Functions
• IV. The Requirement for TFIID In Vivo
• V. Regulation of TFIID
• VI. The TFIID-Chromatin Connection
• VII. Future Questions
• References
• Chapter 4. Tetratricopeptide Repeats of TFC4 and a Limiting Step in the Assembly of the Initiation Factor TFIIIB
• I. Introduction
• II. Brf1-TFIIIC: A Limiting Interaction in Preinitiation Complex Assembly
• III. Brf1-Tfc4 Interactions
• IV. Bdp1-Tfc4 Interactions
• V. Ligand Binding by TPR Arrays in Tfc4
• VI. Ordered Binding of TFIIIB Subunits to TFIIIC-DNA and Dynamic Interactions with Tfc4
• VII. Tfc4 and Other Pol III Factors
• VIII. Conclusion
• References
• Chapter 5. Mechanism of RNA Polymerase I Transcription
• I. Introduction
• II. Ribosomal DNA Gene Structure
• III. Species-Specificity of Ribosomal RNA Transcription
• IV. Factors Involved in Ribosomal RNA Transcription
• V. Assembly of an RNA Polymerase I Initiation Complex in Vertebrates
• VI. Factors Required for RNA Polymerase I Transcription in Yeast
• VII. Regulatory Mechanisms
• VIII. Chromatin and RNA Polymerase I Transcription
• IX. Conclusions
• Acknowledgments
• References
• Chapter 6. Functional Properties of ATP-Dependent Chromatin Remodeling Enzymes
• I. Introduction
• II. History of Nucleosome-Remodeling Complexes
• III. Requirements for Nucleosome-Remodeling Enzymes
• IV. Mechanisms of ATP-Dependent Chromatin Remodeling
• V. Initiation of ATP-Dependent Chromatin Remodeling
• VI. Conclusions
• Acknowledgments
• References
• Chapter 7. Histone Acetyltransferase Proteins Contribute to Transcriptional Processes at Multiple Levels
• I. Introduction
• II. HATs and HAT Complexes: New Insights into HAT Regulation and Effects on Transcription
• III. HAT Complexes Functionally Interact with Chromatin- Remodeling Complexes and Influence Transcription
• IV. HAT Proteins Function in Regulating Transcriptional Elongation
• V. The Histone Code: Insights into Epigenetic Regulation of Transcription
• VI. HATs: New Insight into Transcription and DNA Repair
• VII. Conclusion and Perspectives
• Acknowledgments
• References
• Chapter 8. Posttranslational Modifications of Histones by Methylation
• I. Introduction
• II. Lysine Methyltransferases
• III. Arginine Methyltransferases
• IV. Epilogue
• References
• Author Index.