T cell subsets: cellular selection, commitment and identity /

• Άλλοι συγγραφείς: Cantor, H., Glimcher, Laurie, Alt, Frederick W.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Amsterdam ; Boston : Elsevier Academic Press, ©2004.
• Σειρά: Advances in immunology ; v. 83.
• Θέματα: T cells.; MEDICAL > Immunology.; T-lymfocyten.; T-Lymphocyte Subsets.; Electronic books.

 This first thematic issue, of the Advances in Immunology series, highlights the remarkable new insights into the mechanisms that govern development and function of T cell lineages. Recent developments in the understanding of the genetic and epigenetic mechanisms that regulate development of the two major T cell lineages will have a fundamental impact on a number of research fields -immunology, cell biology, hematology and stem cell research. All of these groups have a vested interest in comprehending issues such as stem cell self renewal, progenitor plasticity, lineage commitment and cellular. 

 Lineage commitment and developmental plasticity in early lymphoid progenitor subsets / David Traver and Koichi Akashi -- The CD4/CD8 lineage choice: new insights into epigenetic regulation during T cell development / Ichiro Taniuchi, Wilfried Ellmeier, and Dan R. Littman -- CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision / Alfred Singer and Remy Bosselut -- Development and function of T helper 1 cells / Anne O'Garra and Douglas Robinson -- Th2 cells: orchestrating barrier immunity / Daniel B. Stetson [and others] -- Generation, maintenance, and function of memory T cells / Patrick R. Burkett [and others] -- CD8+ effector cells / Pierre A. Henkart and Marta Catalfamo -- An integrated model of immunoregulation mediated by regulatory T cell subsets / Hong Jiang and Leonard Chess.