Retroviral proteases /

Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design.

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Kuo, Lawrence C., Shafer, Jules A.
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: San Diego : Academic Press, ©1994.
Σειρά:Methods in enzymology ; v. 241.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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245 0 0 |a Retroviral proteases /  |c edited by Lawrence C. Kuo, Jules A. Shafer. 
260 |a San Diego :  |b Academic Press,  |c ©1994. 
300 |a 1 online resource (xxv, 432 pages, [10] pages of plates) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
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490 1 |a Methods in enzymology,  |x 0076-6879 ;  |v v. 241 
504 |a Includes bibliographical references and indexes. 
588 0 |a Print version record. 
520 |a Methods included in this volume apply to the expression and characterization of retroviral proteases and their inhibitor/substrate design. 
505 0 0 |t 1. Expression Systems for Retroviral Proteases /  |r Jeffrey Stebbins and Christine Debouck --  |t 2. Genetic Approaches Designed to Minimize Cytotoxicity of Retroviral Protease /  |r C.J. Rizzo and B.D. Korant --  |t 3. Host Strain Selection for Bacterial Expression of Toxic Proteins /  |r Elizabeth Chen --  |t 4. Assay Methods for Retroviral Proteases /  |r Christopher U.T. Hellen --  |t 5. Analysis of Human Immunodeficiency Virus Type 1 Protease Activity in Eukaryotic and Bacterial Cells /  |r Andrew H. Kaplan, Marianne Manchester, Lorraine Everitt and Ronald Swanstrom --  |t 6. Synthetic Approaches to Continuous Assays of Retroviral Proteases /  |r Grant A. Krafft and Gary T. Wang --  |t 7. Identification, Purification, and Cell Culture Assays of Retroviral Proteases /  |r Klaus von der Helm, Sigrio Seelmeier, Alexei Kisselev and Hans Nitschko --  |t 8. Stability of Dimeric Retroviral Proteases /  |r Paul L. Darke. 
505 0 0 |t 9. Use of Steady State Kinetic Methods to Elucidate the Kinetic and Chemical Mechanisms of Retroviral Proteases /  |r Thomas D. Meek, Evelyn J. Rodriguez and Thelma S. Angeles --  |t 10. X-Ray Structures of Retroviral Proteases and Their Inhibitor-Bound Complexes /  |r Dagmar Ringe --  |t 11. Probing Structure-Function Relationships in Human Immunodeficiency Virus Type 1 Protease via Molecular Dynamics Simulation /  |r William E. Harte, Jr. and David L. Beveridge --  |t 12. Relationships of Human Immunodeficiency Virus Protease with Eukaryotic Aspartic Proteases /  |r Xin-Li Lin, Ying-Zhang Lin and Jordan Tang --  |t 13. Processing of Retroviral Gag Polyproteins: An in Vitro Approach /  |r Carol Carter and Gabriele Zybarth --  |t 14. Subsite Preferences of Retroviral Proteinases /  |r Ben M. Dunn, Alla Gustchina, Alexander Wlodawer and John Kay --  |t 15. Specificity of Retroviral Proteases: An Analysis of Viral and Nonviral Protein Substrates /  |r Alfredo G. Tomasselli and Robert L. Heinrikson. 
505 0 0 |t 16. Rapid Determination of Endoprotease Specificity Using Peptide Mixtures and Edman Degradation Analysis /  |r Frank R. Masiarz and Bruce A. Malcolm --  |t 17. Design of Tight-Binding Human Immunodeficiency Virus Type 1 Protease Inhibitors /  |r Joseph P. Vacca --  |t 18. Design of Symmetry-Based, Peptidomimetic Inhibitors of Human Immunodeficiency Virus Protease /  |r Dale J. Kempf --  |t 19. Advances in Automated Docking Applied to Human Immunodeficiency Virus Type 1 Protease /  |r Michael D. Miller, Robert P. Sheridan, Simon K. Kearsley and Dennis J. Underwood --  |t 20. Use of Molecular Dynamics and Free Energy Perturbation Calculations in Anti-Human Immunodeficiency Virus Drug Design /  |r Margaret A. McCarrick and Peter Kollman --  |t 21. Qualitative Study of Drug Resistance in Retroviral Protease Using Structural Modeling and Site-Directed Mutagenesis /  |r J. Chris Culberson, Bruce L. Bush and Vinod V. Sardana. 
506 |3 Use copy  |f Restrictions unspecified  |2 star  |5 MiAaHDL 
533 |a Electronic reproduction.  |b [S.l.] :  |c HathiTrust Digital Library,  |d 2011.  |5 MiAaHDL 
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650 0 |a Proteolytic enzymes. 
650 0 |a Retroviruses  |x Enzymes. 
650 0 |a HIV (Viruses) 
650 6 |a Enzymes protéolytiques. 
650 6 |a Rétrovirus  |x Enzymes. 
650 6 |a Virus de l'immunodéficience humaine. 
650 7 |a HIV (Viruses)  |2 fast  |0 (OCoLC)fst00949837 
650 7 |a Proteolytic enzymes.  |2 fast  |0 (OCoLC)fst01079783 
650 7 |a Retroviruses  |x Enzymes.  |2 fast  |0 (OCoLC)fst01096407 
650 1 7 |a Proteïnasen.  |2 gtt 
650 1 7 |a Retrovirussen.  |2 gtt 
650 1 7 |a HIV.  |2 gtt 
650 7 |a Proteasen  |2 gnd  |0 (DE-588)4047521-9 
650 7 |a Retroviren  |2 gnd  |0 (DE-588)4121587-4 
650 7 |a Aufsatzsammlung  |2 gnd  |0 (DE-588)4143413-4 
650 7 |a Enzymologia  |v podręczniki laboratoryjne.  |2 jhpk 
650 0 2 |a Peptide Hydrolases [MESH] 
650 0 2 |a Retroviridae [MESH] 
650 0 2 |a HIV [MESH] 
653 0 |a Enzymes  |a Related to  |a Viruses 
655 4 |a Electronic books. 
655 7 |a Electronic books.  |2 lcgft 
700 1 |a Kuo, Lawrence C. 
700 1 |a Shafer, Jules A. 
776 0 8 |i Print version:  |t Retroviral proteases.  |d San Diego : Academic Press, ©1994  |z 0121821420  |w (OCoLC)31189255 
830 0 |a Methods in enzymology ;  |v v. 241.  |x 0076-6879 
856 4 0 |u https://www.sciencedirect.com/science/bookseries/00766879/241  |z Full Text via HEAL-Link