Nuclear receptors /

• Other Authors: Russell, David W. (David William), 1957-, Mangelsdorf, David J. (David John), 1958-
• Format: eBook
• Language: English
• Published: Amsterdam ; Boston : Elsevier Academic Press, ©2003.
• Series: Methods in enzymology ; v. 364.
• Subjects: Nuclear receptors (Biochemistry); Receptor-ligand complexes.; Nuclear receptors (Biochemistry) > Handbooks, manuals, etc.; SCIENCE > Life Sciences > Biochemistry.; Biofísica.; Receptors, Cytoplasmic and Nuclear.; Hormones.; Ligands.; Electronic books.; Handbooks and manuals.; Laboratory Manuals.

Nuclear Receptors are inducible transcription factors that mediate complex effects on development, differentiation and homeostasis. They regulate the transcription of their target genes through binding to DNA sequences.

Table of Contents:

• Analysis of nuclear receptor ligands
• Structure/function analysis of nuclear receptors
• Analysis of nuclear receptor cofactors and chromatin remodeling
• Identification of nuclear receptor target genes and effectors
• Use of animal models to study nuclear receptor function.