Ubiquitin and protein degradation. Part A /

• Other Authors: Deshaies, Raymond Joseph, 1961-
• Format: eBook
• Language: English
• Published: Amsterdam ; Boston : Elsevier Academic Press, ©2005.
• Series: Methods in enzymology ; v. 398.
• Subjects: Ubiquitin.; Proteins > Metabolism.; Ubiquitine.; Protéines > Métabolisme.; Eiwitten.; Ontleding (scheikunde); Proteins > metabolism.; Ubiquitins > physiology.; Electronic books.

Ubiquitin and Protein Degradation, Part B will cover chemical biology, ubiquitin derivatives and ubiquitin-like proteins, deubiquitinating enzymes, proteomics as well as techniques to monitor protein degradation. The chapters are highly methodological and focus on application of techniques. *Second...

Table of Contents:

• pt. A. E1 enzyme ; E2 enzyme ; E3 enzyme ; Proteasome ; Isopeptidases
• pt. B. Ubiquitin and ubiquitin derivatives ; Ubiquitin binding domains ; Methods to study the Proteasome ; Identification and characterization of substrates and ubiquitin ligases ; Genome and proteome-wide approaches to identify substrates and enzymes ; Real time/non-invasive technologies ; Small molecule inhibitors ; Generally applicable technologies.