Macromolecular crystallography. Part C /

Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodologi...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Carter, Charles W., Sweet, Robert M.
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Amsterdam ; Oxford : Elsevier Academic Press, Ã2003.
Σειρά:Methods in enzymology ; v. 368.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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020 |a 0080497098  |q (electronic bk.) 
020 |a 9780080497099  |q (electronic bk.) 
020 |a 0121822710  |q (electronic bk.) 
020 |a 9780121822712  |q (electronic bk.) 
035 |a (OCoLC)441778930 
050 4 |a QP601 
060 4 |a QU135  |b MET 
082 0 4 |a 548.3  |2 21 
049 |a TEFA 
245 0 0 |a Macromolecular crystallography.  |n Part C /  |c edited by Charles W. Carter, Jr., Robert M. Sweet. 
260 |a Amsterdam ;  |a Oxford :  |b Elsevier Academic Press,  |c Ã2003. 
300 |a 1 online resource (xxxii, 368 pages, [4] pages of plates) :  |b illustrations (some color). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Methods in enzymology ;  |v v. 368 
504 |a Includes bibliographical references and index. 
505 0 |a Cover -- Table of Contents -- Contributor to Volume 368 -- Preface -- Volumes in Series -- Section I: Reminiscences on Methods -- Chapter 1. Transformations in Structural Biology: Personal View -- Chapter 2. Origins -- Chapter 3. Personal X-ray Reflections -- Section II: Crystals -- Chapter 4. Robotics for Automated Crystal Formation and Analysis -- Chapter 5. Use of Limited Proteolysis to Identify Protein Domains Suitable for Structural Analysis -- Chapter 6. Solvent Entropy Effects in the Formation of Protein Solid Phases -- Chapter 7. Controlling Biomolecular Crystallization by Understanding the Distinct Effects of PEGs and Salts on Solubility -- Chapter 8. Counter-diffusion Methods for Macromolecular Crystallization -- Chapter 9. Growth Sectors and Crystal Quality -- Chapter 10. Molecular Mechanisms of Defect Formation -- Chapter 11. Cryocooling of Macromolecular Crystals: Optimization Methods -- Chapter 12. The Well-Tempered Protein Crystal:Annealing Macromolecular Crystals -- Section III: Data -- Chapter 13. What Can I Have As a Source of X-Ray Synchrotron Radiation? A Primer for Potential Users -- Chapter 14. Protein Crystal Structure Analysis from High- Resolution X-Ray Powder-Diffraction Data -- Chapter 15. Macromolecular Crystal Quality -- Chapter 16. Protein Structures at Atomic Resolution -- Author Index -- Subject Index -- Color Plates Section -- Last Page. 
520 |a Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding. * Methodological methods in crystals * Methodological methods data analysis. 
588 0 |a Print version record. 
650 0 |a X-ray crystallography. 
650 0 |a Enzymes  |x Analysis. 
650 0 |a Proteins  |x Analysis. 
650 7 |a Enzymes  |x Analysis.  |2 fast  |0 (OCoLC)fst00913606 
650 7 |a Proteins  |x Analysis.  |2 fast  |0 (OCoLC)fst01079714 
650 7 |a X-ray crystallography.  |2 fast  |0 (OCoLC)fst01181820 
650 0 2 |a Macromolecular Substances [MESH] 
650 0 2 |a Crystallography [MESH] 
655 4 |a Electronic books. 
700 1 |a Carter, Charles W. 
700 1 |a Sweet, Robert M. 
830 0 |a Methods in enzymology ;  |v v. 368. 
856 4 0 |u https://www.sciencedirect.com/science/bookseries/00766879/368  |z Full Text via HEAL-Link