Protein modules and protein-protein interaction /

• Άλλοι συγγραφείς: Janin, Joël, Wodak, Shoshana J.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Amsterdam ; Boston : Academic Press, ©2002.
• Σειρά: Advances in protein chemistry ; v. 61.
• Θέματα: Proteins > Conformation.; Molecular recognition.; Proteins > genetics.; Protein Conformation.; Proteins > chemistry.; Proteins > physiology.; Electronic books.

 Protein modules engage in a multitude of interactions with one another and with other cellular components, notably with DNA. These interactions are a central aspect of protein function of great relevance in the post-genomic era. This volume describes a panel of approaches for analyzing protein modules and their interactions, ranging from bioinformatics to physical chemistry, to biochemistry, with an emphasis on the structure-function relationship in protein-protein complexes involved in cellular processes including signal transduction. Key Features: Comprehensive overview of different facets of macromolecule interactions. Computational and bioinformatics aspects of analyzing protein modules and their interactions. Emphasis on structure-function relationship in protein-protein complexes involved in cellular processes. 

 Structural basis of macromolecular recognition /   Shoshana J. Wodak and Joël Janin --   Sequence analysis of multidomain proteins: past perspectives and future directions /   Richard R. Copley [and others] --   Identification of transiently interacting proteins and of stable protein complexes /   Bertrand Séraphin --   Molecular recognition in antibody-antigen complexes /   Eric J. Sundberg and Roy A. Mariuzza --   Molecular recognition by SH2 domains /   J. Michael Bradshaw and Gabriel Waksman --   How SH3 domains recognize proline /   Andrea Musacchio --   Structural biology of elF4F: mRNA recognition and preparation in eukaryotic translation initiation /   Joseph Marcotrigiano and Stephen K. Burley.