Functional genomics and proteomics in the clinical neurosciences /

• Άλλοι συγγραφείς: Hemby, S. E. (Επιμελητής έκδοσης), Bahn, Sabine (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Amsterdam ; Boston : Elsevier, 2006.
• Έκδοση: 1st edition.
• Σειρά: Progress in brain research ; v. 158.
• Θέματα: Neurobehavioral disorders > Genetic aspects.; Neurobehavioral disorders > Molecular aspects.; Messenger RNA > Analysis.; Proteins > Analysis.; Gene expression > Research.; Genomics.; Proteomics.; Neurogenetics.; Nervous System Diseases > genetics.; Genomics > methods.; Proteomics > methods.; Neurogénétique > Méthodologie.; Protéomique > Méthodologie.; Système nerveux > Maladies > Aspect génétique.; HEALTH & FITNESS > Diseases > General.; MEDICAL > Clinical Medicine.; MEDICAL > Diseases.; MEDICAL > Evidence-Based Medicine.; MEDICAL > Internal Medicine.; Genomica.; Proteomica.; Neurowetenschappen.; Electronic books.
• Φυσική περιγραφή: 1 online resource (x, 317 pages) : illustrations (some color).
• Βιβλιογραφία: Includes bibliographical references and index.
• ISBN: 9780080465630; 0080465633; 0444518533; 9780444518538
• ISSN: 0079-6123 ;

The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression.