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05060nam a2200805 4500 |
| 001 |
ocn659562187 |
| 003 |
OCoLC |
| 005 |
20180501121934.0 |
| 006 |
m o d |
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4 |
|a RC455.4.G4
|b F86 2006eb
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| 060 |
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4 |
|a W1
|b PR667J v.158 2006
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| 060 |
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4 |
|a WL 140
|b F978 2006
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|2 bisacsh
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|
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|a MED
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|2 bisacsh
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|
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4 |
|a 616.8
|2 22
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| 049 |
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|a TEFA
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| 245 |
0 |
0 |
|a Functional genomics and proteomics in the clinical neurosciences /
|c edited by S.E. Hemby, S. Bahn.
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| 250 |
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|a 1st edition.
|
| 264 |
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1 |
|a Amsterdam ;
|a Boston :
|b Elsevier,
|c 2006.
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| 300 |
|
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|a 1 online resource (x, 317 pages) :
|b illustrations (some color).
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
|
| 337 |
|
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|a computer
|b c
|2 rdamedia
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| 338 |
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Progress in brain research,
|x 0079-6123 ;
|v volume 158
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| 504 |
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|a Includes bibliographical references and index.
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| 505 |
0 |
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|a Section I: Methodologies -- Tissue preparation and banking -- Functional genomic methodologies -- Methods for proteomics in neuroscience -- Functional genomics and proteomics in the clinical neurosciences: data mining and bioinformatics -- Reproducibility of microarray studies: concordance of current analysis methods -- Introduction -- Section II: Applications of Genomics and Proteomic Technologies to Clinical Neuroscience -- The genomics of mood disorders -- Assessment of genome and proteome profiles in cocaine abuse -- Neuronal gene expression profiling: uncovering the molecular biology of neurodegenerative disease -- Epileptogenesis-related genes revisited -- Functional genomics of sex hormone-dependent neuroendocring systems: specific and generalized actions in the CNS -- Section III: Future Directions -- Implications for the practice of psychiatry -- Human brain evolution.
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| 520 |
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|a The purpose of this work is to familiarize neuroscientists with the available tools for proteome research and their relative abilities and limitations. To know the identities of the thousands of different proteins in a cell, and the modifications to these proteins, along with how the amounts of both of these change in different conditions would revolutionize biology and medicine. While important strides are being made towards achieving the goal of global mRNA analysis, mRNA is not the functional endpoint of gene expression and mRNA expression may not directly equate with protein expression.
|
| 588 |
0 |
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|a Print version record.
|
| 650 |
|
0 |
|a Neurobehavioral disorders
|x Genetic aspects.
|
| 650 |
|
0 |
|a Neurobehavioral disorders
|x Molecular aspects.
|
| 650 |
|
0 |
|a Messenger RNA
|x Analysis.
|
| 650 |
|
0 |
|a Proteins
|x Analysis.
|
| 650 |
|
0 |
|a Gene expression
|x Research.
|
| 650 |
|
0 |
|a Genomics.
|
| 650 |
|
0 |
|a Proteomics.
|
| 650 |
|
0 |
|a Neurogenetics.
|
| 650 |
1 |
2 |
|a Nervous System Diseases
|x genetics.
|0 (DNLM)D009422Q000235
|
| 650 |
2 |
2 |
|a Genomics
|x methods.
|0 (DNLM)D023281Q000379
|
| 650 |
2 |
2 |
|a Proteomics
|x methods.
|0 (DNLM)D040901Q000379
|
| 650 |
|
6 |
|a Neurogénétique
|x Méthodologie.
|
| 650 |
|
6 |
|a Protéomique
|x Méthodologie.
|
| 650 |
|
6 |
|a Système nerveux
|x Maladies
|x Aspect génétique.
|
| 650 |
|
7 |
|a HEALTH & FITNESS
|x Diseases
|x General.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Clinical Medicine.
|2 bisacsh
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| 650 |
|
7 |
|a MEDICAL
|x Diseases.
|2 bisacsh
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| 650 |
|
7 |
|a MEDICAL
|x Evidence-Based Medicine.
|2 bisacsh
|
| 650 |
|
7 |
|a MEDICAL
|x Internal Medicine.
|2 bisacsh
|
| 650 |
1 |
7 |
|a Genomica.
|2 gtt
|
| 650 |
1 |
7 |
|a Proteomica.
|2 gtt
|
| 650 |
1 |
7 |
|a Neurowetenschappen.
|2 gtt
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
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|a Hemby, S. E.,
|e editor.
|
| 700 |
1 |
|
|a Bahn, Sabine,
|e editor.
|
| 776 |
0 |
8 |
|i Print version:
|t Functional genomics and proteomics in the clinical neurosciences.
|b 1st ed.
|d Amsterdam ; Boston : Elsevier, 2006
|z 9780444518538
|w (DLC) 2006048508
|w (OCoLC)70408040
|
| 830 |
|
0 |
|a Progress in brain research ;
|v v. 158.
|
| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00796123/158
|z Full Text via HEAL-Link
|
