Functional glycomics /

• Άλλοι συγγραφείς: Fukuda, Minoru, 1945-
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego, Calif : Academic Press/Elsevier, ©2010.
• Σειρά: Methods in enzymology ; v. 479.
• Θέματα: Glycomics.; Glycosylation.; Electronic books.

 In this 3 volume collection focusing on glycomics, readers will appreciate how such discoveries were made and how such methods can be applied for readers' own research efforts Each chapter has been designed so that enough scientific background will be given in each chapter for further development of methods by readers themselves. Useful for all levels of scientists starting from the last years of colleges, graduate students, postdoctoral fellows to professors and to all levels of scientists in research institutes including industry. 

 [Beta]1,4-galactosyltransferase V: a growth regulator in glioma / Jianhai Jiang and Jianxin Gu -- Roles of polysialic acid in migration and differentiation of neural stem cells / Kiyohiko Angata and Minoru Fukuda -- Structural and functional analysis of chondroitin sulfate proteoglycans in the neural stem cell niche / Swetlana Sirko [and others] -- Transcript analysis of stem cells / Alison V. Nairn, Mitche dela Rosa and Kelley W. Moremen -- Directing stem cell trafficking via GPS / Robert Sackstein -- Functional assays for the molecular chaperone cosmc / Tongzhong Ju and Richard D. Cummings -- Core 3-derived O-glycans are essential for intestinal mucus barrier function / Lijun Xia -- Core3 glycan as tumor suppressor / Seung Ho Lee and Minoru Fukuda -- Characterization of mice with targeted deletion of the gene encoding core 2 [beta]1,6-N-acetylglucosaminyltransferase-2 / Erica L. Stone [and others] -- Analyzing physiological function of polypeptide GalNAcT-1-deficient mice in humoral immunity / Mari Tenno -- [beta]3GnT2 (B3GNT2), a major polylactosamine synthase: analysis of B3gnt2-deficient mice / Akira Togayachi ... [er al.] -- Targeted genetic inactivation of N-acetylglucosaminyltransferase-IVa impairs insulin secretion from pancreatic [beta] cells and evokes type 2 diabetes / Kazuaki Ohtsuboa -- The Ashwell-Morell receptor / Prabhjit K. Grewal -- Roles of GlcNAc-6-O-sulfotransferases in lymphoid and nonlymphoid tissues / Hiroto Kawashima -- Core O-glycans required for lymphocyte homing: gene knockout mice of core 1 [beta]1,3-N-acetylglucosaminyltransferase and core 2 N-acetylglucosaminyltransferase / Junya Mitoma and Minoru Fukuda -- Immunohistochemical analysis of carbohydrate antigens in chronic inflammatory gastrointestinal diseases / Motohiro Kobayashi and Jun Nakayama -- Genetic defects in muscular dystrophy / Kumaran Chandrasekharan and Paul T. Martin -- POMT1 is essential for protein O-mannosylation in mammals / Mark Lommel [and others] -- POMGnT1, POMT1, and POMT2 mutations in congenital muscular dystrophies / Tamao Endo [and others] -- Cellular and molecular characterization of abnormal brain development in protein O-mannose N-acetylglucosaminyltransferase 1 knockout mice / Jianmin Liu [and others] -- Investigating the functions of LARGE: lessons from mutant mice / Jane E. Hewitt -- A tumor suppressor function of laminin-binding [alpha]-dystroglycan / Xingfeng Bao and Minoru Fukuda -- Tumor formation assays / Shingo Hatakeyama, Hayato Yamamoto and Chikara Ohyama.