Structure, function and regulation of Tor complexes from yeasts to mammals. Part A /
Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in turn causes developmental errors and a wide range of pathological conditions. An understanding of the TOR signaling netwo...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Amsterdam ; Boston :
Academic Press,
2010.
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| Edition: | 1st ed. |
| Series: | Enzymes ;
v. 27. |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
| Summary: | Cell growth is highly regulated and is controlled by the TOR signaling network. Dysfunction of signaling pathways controlling cell growth results in cells of altered sizes and in turn causes developmental errors and a wide range of pathological conditions. An understanding of the TOR signaling network may lead to novel drugs for the treatment of, for example, €cancer, diabetes, inflammation, muscle atrophy, learning disabilities, depression, obesity and aging. There has been an explosion of knowledge in this area in recent years and this volume provides an in-depth review of our current knowledge of TOR complexes by the leadersin the field. |
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| Physical Description: | 1 online resource (xii, 404 pages, [4] pages of plates) : illustrations (some color). |
| Bibliography: | Includes bibliographical references and indexes. |
| ISBN: | 9780123815408 0123815401 9780123815392 0123815398 |
