Notch Signaling /

• Other Authors: Kopan, Raphael (Editor)
• Format: eBook
• Language: English
• Published: San Diego, CA : Academic, 2010.
• Edition: First edition.
• Series: Current topics in developmental biology ; v. 92.
• Subjects: Notch proteins.; Notch genes.; Cellular signal transduction.; Receptors, Notch > genetics.; Receptors, Notch > therapeutic use.; Signal Transduction.; SCIENCE > Life Sciences > Cell Biology.; Electronic books.

International authors provide researchers with an overview and synthesis of the latest research findings and contemporary thought in the area of Notch Signaling. Covers topics such as Notch signaling in Cardiac development and disease, and Notch in Stem Cells. International authors provide researche...

Table of Contents:

• Cover; International Review of; Copyright; Contents; Contributors; Prologue; Chapter 1. Notch: The Past, the Present, and the Future; Chapter 2. Mechanistic Insights into Notch Receptor Signaling fromStructural and Biochemical Studies; Chapter 3. Canonical and Non-Canonical Notch Ligands; Chapter 4. Roles of Glycosylation in Notch Signaling; Chapter 5. Endocytosis and Intracellular Trafficking of Notchand Its Ligands; Chapter 6. y-Secretase and the Intramembrane Proteolysis of Notch; Chapter 7. Two Opposing Roles of RBP-J in Notch Signaling; Chapter 8. Notch Targets and Their Regulation.