|
|
|
|
| LEADER |
04524nam a2200505 4500 |
| 001 |
ocn698384528 |
| 003 |
OCoLC |
| 005 |
20180501121939.0 |
| 006 |
m o d |
| 007 |
cr cnu---unuuu |
| 008 |
110126s2010 ne a ob 001 0 eng d |
| 040 |
|
|
|a COF
|b eng
|e pn
|c COF
|d OCLCQ
|d OPELS
|d OCLCQ
|d OCLCF
|d EBLCP
|d OCLCQ
|d GrThAP
|
| 019 |
|
|
|a 813292924
|
| 020 |
|
|
|a 9780444537515
|q (electronic bk.)
|
| 020 |
|
|
|a 0444537511
|q (electronic bk.)
|
| 020 |
|
|
|a 9780444537508
|q (electronic bk.)
|
| 020 |
|
|
|a 0444537503
|q (electronic bk.)
|
| 035 |
|
|
|a (OCoLC)698384528
|z (OCoLC)813292924
|
| 050 |
|
4 |
|a RC382
|
| 082 |
0 |
4 |
|a 616.8330072
|2 22
|
| 049 |
|
|
|a TEFA
|
| 245 |
0 |
0 |
|a Recent advances in Parkinson's disease /
|c edited by Anders Björklund, M. Angela Cenci.
|
| 250 |
|
|
|a 1st ed.
|
| 260 |
|
|
|a Amsterdam ;
|a Boston :
|b Elsevier,
|c 2010.
|
| 300 |
|
|
|a 1 online resource (2 volumes) :
|b illustrations.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Progress in brain research,
|x 0079-6123 ;
|v v. 184
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 588 |
0 |
|
|a Print version record.
|
| 520 |
|
|
|a This second volume follows on from Part I by reviewing the variety of animal models of PD current available (from drosophila to rodents to non-human primate species) and their specific contributions to PD research. This is followed by comprehensive coverage of functional neuroimaging studies that explore different pathophysiological questions and evaluate treatment outcome in PD patients. Different areas of experimental therapeutics and outstanding challenges to PD treatment are presented in a concluding group of articles. Complete overview of hot topics and approaches to current PD research, from molecules, to brain circuits, to clinical and therapeutic applications. Leading authors review the state-of-the-art in their field of investigation, and provide their views and perspectives for future research. All chapters include comprehensive background information and are written in a clear form that is accessible also to the non-specialist.
|
| 505 |
0 |
|
|a Cover; Recent Advances in Parkinson's Disease: Translational and Clinical Research; Copyright; List of Contributors; Preface; Contents; Section I. Animal models of PD; Chapter 1. What have we learned from Drosophila models of Parkinson's disease?; Chapter 2. Neurotoxic in vivo models of Parkinson's disease: recent advances; Chapter 3. Behavioral analysis of motor and non-motor symptoms in rodent models of Parkinson's disease; Chapter 4. Genetic mouse models of Parkinson's disease: The state of the art.
|
| 505 |
8 |
|
|a Chapter 5. Viral vector-mediated overexpression of a-synuclein as a progressive model ofParkinson's diseaseChapter 6. Modeling neuroinflammatory pathogenesis of Parkinson's disease; Chapter 7. The MPTP-lesioned non-human primate models of Parkinson's disease. Past, present, and future; Section II. Exploring PD with brain imaging; Chapter 8. Abnormal metabolic brain networks in Parkinson's disease: from blackboard to bedside; Chapter 9. Imaging the nigrostriatal system to monitor disease progression andtreatment-induced complications; Chapter 10. Brain imaging after neural transplantation.
|
| 505 |
8 |
|
|a Chapter 11. Imaging non-motor aspects of Parkinson's diseaseSection III. Frontiers in PD treatment; Chapter 12. Gene therapy for dopamine replacement; Chapter 13. Neurotrophic factor therapy for Parkinson's disease; Chapter 14. Neural grafting in Parkinson's disease: problems and possibilities; Chapter 15. Neural grafting in Parkinson's disease: unraveling the mechanisms underlyinggraft-induced dyskinesia; Chapter 16. Deep brain stimulation: state of the art and novel stimulation targets; Chapter 17. The challenge of non-motor symptoms in Parkinson's disease; Subject Index.
|
| 650 |
|
0 |
|a Parkinson's disease.
|
| 650 |
|
0 |
|a Neurosciences
|x Research.
|
| 650 |
|
7 |
|a Neurosciences
|x Research.
|2 fast
|0 (OCoLC)fst01036518
|
| 650 |
|
7 |
|a Parkinson's disease.
|2 fast
|0 (OCoLC)fst01053693
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
|
|a Björklund, Anders,
|d 1945-
|
| 700 |
1 |
|
|a Cenci, M. Angela.
|
| 776 |
0 |
8 |
|i Print version:
|a Bjorklund, Anders.
|t Recent Advances in Parkinsons Disease : Translational and clinical research.
|d Burlington : Elsevier, ©2010
|z 9780444537508
|
| 830 |
|
0 |
|a Progress in brain research ;
|v v. 184.
|
| 856 |
4 |
0 |
|u https://www.sciencedirect.com/science/bookseries/00796123/184
|z Full Text via HEAL-Link
|
