Biothermodynamics. Part C /

• Other Authors: Johnson, Michael L., 1947-, Holt, Jo M., Ackers, Gary K.
• Format: eBook
• Language: English
• Published: Amsterdam [Netherlands] ; Boston [Mass.] : Elsevier/Academic Press, 2011.
• Edition: 1st ed.
• Series: Methods in enzymology ; v. 488.
• Subjects: Thermodynamics.; Protein binding.; Protein-protein interactions.; Ligands (Biochemistry); SCIENCE > Life Sciences > Biochemistry.; Protein Binding.; Hemoglobins.; Ligands.; Electronic books.
• Physical Description: 1 online resource (xlv, 354 pages, [8] pages of plates) : illustrations (some color).
• Bibliography: Includes bibliographical references and indexes.
• ISBN: 9780123812681; 0123812682
• ISSN: 0076-6879 ;

The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules.