Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors /

"Since its discovery in 1958, the Catechol-O-methyltransferase (COMT) enzyme has generated a lot of excitement, particularly so in more recent years with the discovery of clinically relevant COMT inhibitors in the late 1980's. While the volume of published research on the COMT enzyme and i...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Nissinen, Erkki (Επιμελητής έκδοσης)
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Amsterdam ; Boston : Elsevier/Academic Press, 2010.
Σειρά:International review of neurobiology ; v. 95.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03425nam a2200589 4500
001 ocn702118872
003 OCoLC
005 20180501121939.0
006 m o d
007 cr cnu---unuuu
008 110216s2010 ne a ob 001 0 eng d
040 |a N$T  |b eng  |e pn  |c N$T  |d QCL  |d CDX  |d UKMGB  |d OCLCQ  |d OPELS  |d OCLCQ  |d YDXCP  |d OPELS  |d OCLCF  |d IDEBK  |d OCLCQ  |d MEU  |d FEM  |d GrThAP 
016 7 |a 015617994  |2 Uk 
019 |a 688973486  |a 823849533  |a 823919467  |a 824102492  |a 824163144  |a 968112136  |a 969014941 
020 |a 9780123813275  |q (electronic bk.) 
020 |a 0123813271  |q (electronic bk.) 
020 |a 9780123813268  |q (electronic bk.) 
020 |a 0123813263  |q (electronic bk.) 
020 |a 1282954881 
020 |a 9781282954885 
035 |a (OCoLC)702118872  |z (OCoLC)688973486  |z (OCoLC)823849533  |z (OCoLC)823919467  |z (OCoLC)824102492  |z (OCoLC)824163144  |z (OCoLC)968112136  |z (OCoLC)969014941 
050 4 |a QP981.C25  |b B37 2010eb 
072 7 |a MED  |x 093000  |2 bisacsh 
072 7 |a MED  |x 105020  |2 bisacsh 
072 7 |a MJN, PSAN  |2 bicssc 
082 0 4 |a 615.788  |2 22 
049 |a TEFA 
245 0 0 |a Basic Aspects of Catechol-O-Methyltransferase and the Clinical Applications of its Inhibitors /  |c edited by Erkki Nissinen. 
264 1 |a Amsterdam ;  |a Boston :  |b Elsevier/Academic Press,  |c 2010. 
300 |a 1 online resource (xii, 323 pages :  |b illustrations). 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
347 |a text file  |2 rda 
490 1 |a International review of neurobiology ;  |v v. 95 
546 |a Text in English. 
520 |a "Since its discovery in 1958, the Catechol-O-methyltransferase (COMT) enzyme has generated a lot of excitement, particularly so in more recent years with the discovery of clinically relevant COMT inhibitors in the late 1980's. While the volume of published research on the COMT enzyme and its inhibitors is substantial, there is no comprehensive, up-to-date source containing all the information available on basic COMT biochemistry and pharmacology, as well as critical review of results from clinical trials. This volume of International Review of Neurobiology summarizes what is currently known about COMT enzyme: its genomics, structure, function and biochemical properties; and presents up-to-date evaluation of the clinical use of COMT inhibitors as an adjunct to levodopa/dopa decarboxylase inhibitor treatment in Parkinson's disease."--Publisher's description. 
504 |a Includes bibliographical references and index. 
588 0 |a Print version record. 
650 0 |a Catecholamines. 
650 0 |a Psychotropic drugs. 
650 0 |a Parkinson's disease  |x Chemotherapy. 
650 7 |a MEDICAL  |x Pain Medicine.  |2 bisacsh 
650 7 |a MEDICAL  |x Psychiatry  |x Psychopharmacology.  |2 bisacsh 
650 7 |a Catecholamines.  |2 fast  |0 (OCoLC)fst00848987 
650 7 |a Parkinson's disease  |x Chemotherapy.  |2 fast  |0 (OCoLC)fst01053695 
650 7 |a Psychotropic drugs.  |2 fast  |0 (OCoLC)fst01081826 
655 4 |a Electronic books. 
700 1 |a Nissinen, Erkki,  |e editor. 
776 0 8 |i Print version:  |t Basic aspects of catechol-O-methyltransferase and the clinical applications of its inhibitors.  |d London : Academic, 2010  |z 9780123813268  |w (OCoLC)653082345 
830 0 |a International review of neurobiology ;  |v v. 95. 
856 4 0 |u https://www.sciencedirect.com/science/bookseries/00747742/95  |z Full Text via HEAL-Link