Biology of serpins /

• Άλλοι συγγραφείς: Whisstock, James C., Bird, Phillip I.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego, CA : Academic Press, 2011.
• Έκδοση: 1st ed.
• Σειρά: Methods in enzymology ; v. 499.
• Θέματα: Serpins.; Proteins.; Protein folding.; Proteins > Biotechnology.; Electronic books.

Serpins are a group of proteins with similar structures that were first identified as a set of proteins able to inhibit proteases. The acronym serpin was originally coined because many serpins inhibit chymotrypsin-like serine proteases. This volume of Methods in Ezymology is split into 2 parts and c...

Πίνακας περιεχομένων:

• Analysis of Serpin Secretion, Misfolding, and Surveillance in the Endoplasmic Reticulum
• Serpin-Enzyme Receptors: LDL Receptor-Related Protein 1
• The Role of Autophagy in Alpha-1-Antitrypsin Deficiency
• Serpins and the Complement System
• Use of Mouse Models to Study Plasminogen Activator Inhibitor-1
• Plasminogen Activator Inhibitor Type 2: Still an Enigmatic Serpin but a Model for Gene Regulation
• The SerpinB1 Knockout Mouse: A Model for Studying Neutrophil Protease Regulation in Homeostasis and Inflammation
• Investigating Maspin in Breast Cancer Progression Using Mouse Models
• Hsp47 as a collagen-specific molecular chaperone
• Assays for the Antiangiogenic and Neurotrophic Serpin Pigment Epithelium-Derived Factor
• The Drosophila Serpins: Multiple Functions in Immunity and Morphogenesis
• Modeling Serpin Conformational Diseases in Drosophila melanogaster
• Using Caenorhabditis elegans to Study Serpinopathies
• Using C. elegans to Identify the Protease Targets of Serpins In Vivo
• Viral Serpin Therapeutics: From Concept to Clinic
• man SCCA Serpins Inhibit Staphylococcal Cysteine Proteases by Forming Classic "Serpin-Like' Covalent Complexes
• Plants and the Study of Serpin Biology.