Comparative pharmacokinetics /
"Now in a newly revised edition, Comparative Pharmacokinetics presents the principles and techniques of pharmacokinetics in a detailed, yet practical and easily understandable manner. Coverage includes an overview of the basic physiologic processes of drug absorption and disposition and detaile...
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| Format: | eBook |
| Language: | English |
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Chichester, West Sussex :
Wiley-Blackwell,
2011.
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| Edition: | 2nd edition. |
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| Online Access: | Full Text via HEAL-Link |
Table of Contents:
- Front Matter
- Introduction
- Principles of Drug Movement in the Body
- Quantitative Structure₆Permeability Relationships / Xin-Rui Xia
- Absorption
- Distribution / Jennifer Buur
- Renal Elimination
- Hepatic Biotransformation and Biliary Excretion / Ronald Baynes
- Compartmental Models
- Noncompartmental Models
- Nonlinear Models
- Physiological Models / Teresa Leavens
- Dosage Regimens
- Simultaneous Pharmacokinetic₆Pharmacodynamic Modeling / Pierre-Louis Toutain
- Study Design and Data Analysis / Jason Chittenden
- Bioequivalence Studies / Marilyn Martinez
- Population Pharmacokinetic Models / Jason Chittenden
- Dosage Adjustments in Disease States / Jennifer Davis
- Interspecies Extrapolations
- Tissue Residues and Withdrawal Times
- Index.
- Machine generated contents note: Preface. Chapter 1: Introduction. Chapter 2: Principles of Drug Movement in the Body. Chapter 3: Quantitative Structure Permeability Relationships (QSPeR). Chapter 4: Absorption. Chapter 5: Distribution. Chapter 6: Renal Elimination. Chapter 7: Hepatic Biotransformation and Biliary Excretion. Chapter 8: Compartmental Models. Chapter 9: Noncompartmental Models. Chapter 10: Nonlinear Models. Chapter 11: Physiological Models. Chapter 12: Dosage Regimens. Chapter 13: Simultaneous Pharmacokinetic-Pharmacodynamic Modeling. Chapter 14: Study Design and Data Analysis. Chapter 15: Design and Analysis of Bioequivalence Studies and FDA's in vitro/in vivo (IVIV). Chapter 16: Population Pharmacokinetic Models and the Bayesian Forecasting Applied to Clinical Pharmacokinetics. Chapter 17: Dosage Adjustments in Renal (and Hepatic) Disease. Chapter 18: Interspecies Extrapolations. Chapter 19: Tissue Residues and Withdrawal TimesAppendix.
