Label-free technologies for drug discovery /

Label-free technologies for drug discovery /

Over the past two decades the benefits of label-free biosensor analysis have begun to make an impact in the market, and systems are beginning to be used as mainstream research tools in many drug discovery laboratories. Label-Free Technologies For Drug Discovery summarises the latest and emerging dev...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Cooper, M. A. (Matthew A.), Mayr, Lorenz
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Chichester, West Sussex, U.K. : John Wiley & Sons, 2011.
Θέματα:
Drug development.
Drug Discovery.
Biosensing Techniques.
Drug Design.
Medicine.
Pharmacy.
MEDICAL > Drug Guides.
MEDICAL > Nursing > Pharmacology.
MEDICAL > Pharmacology.
MEDICAL > Pharmacy.
Electronic books.
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Front Matter
  • The Revolution of Real-Time, Label-Free Biosensor Applications / Rebecca L Rich, David G Myszka
  • Design and Implementation of Vertically Emitting Distributed Feedback Lasers for Biological Sensing / Meng Lu, Steven S Choi, Chun Ge, Clark J Wagner, J Gary Eden, Brian T Cunningham
  • SPR Screening of Chemical Microarrays for Fragment-Based Discovery / Thomas Neumann, Renate Sekul
  • The CellKeyʼ System: A Label-Free Cell-Based Assay Platform for Early Drug Discovery Applications / Ryan P McGuinness, Debra L Gallant, Yen-Wen Chen, Trisha A Tutana, Donna L Wilson, John M Proctor, H Roger Tang
  • Dynamic and Label-Free Cell-Based Assays Using the xCELLigence System / Yama A Abassi, Alexander Sieler, Manfred Watzele, Xiaobo Wang, Xiao Xu
  • Selecting the Best HTS Hits to Move Forward: ITC Ligand Binding Characterization Provides Guidance / Ronan O'Brien, Richard Brown
  • Incorporating Transmitted Light Modalities into High-Content Analysis Assays / Robert Graves
  • Nonradioactive Rubidium Efflux Assay Technology for Screening of Ion Channels / Georg C Terstappen
  • Expanding the Scope of HTMS Methods / Tom G Holt, Jun Wang, Xun Chen, Bernard K Choi, Neil S Geoghagen, Kristian K Jensen, Maxine Jonas, Qi Luo, William A LaMarr, Lorraine Malkowitz, Can C Ozbal, Yusheng Xiong, Claude Dufresne, Ming-Juan Luo
  • A Novel Multiplex SPR Array for Rapid Screening and Affinity Determination of Monoclonal Antibodies: The ProteOn XPR36 Label Free System: Kinetic Screening of Monoclonal Antibodies / Vered Bronner, Oded Nahshol, Tsafrir Bravman
  • Biophysics/Label-Free Assays in Hit Discovery and Verification / Johannes Ottl
  • Harnessing Optical Label-Free on Microtiter Plates for Lead Finding: From Binding to Phenotypes / Julio Martin
  • Use of Label-Free Detection Technologies in the Hit-to-Lead Process: Surface Optical Detection of Cellular Processes / F Stuhmeier, J Bradley, E Fairman, E Gbekor, P Hayter, S Ramsey
  • Cellular Screening for 7TM Receptors Using Label-Free Detection / Jeffrey C Jerman, Jason Brown, Magalie Rocheville
  • Novartis Evaluation of the ForteBio Octet RED: A Versatile Instrument for Direct Binding Experiments / Eric Martin, John Wang, Isabel Zaror, Jiamin Yu, Kelly Yan, Mike Doyle, Paul Feucht, Kevin Shoemaker, Bob Warne, Mike Chin, Blisseth Sy, Lukas Leder, Marco Meyerhofer, Charles Wartchow, Danfeng Yao
  • The Pyramid₉ Approach to Fragment-Based Biophysical Screening / Glyn Williams
  • Characterisation of Antibodies Against the Active Conformation of G Using the SRU-BINDʼ Label-Free Detection System / Melanie Leveridge, Chun-Wa Chung, Trevor Wattam
  • SPR-Based Direct Binding Assays in Drug Discovery / Walter Huber
  • Kinetic Binding Mechanisms: Their Contribution to an Optimal Therapeutic Index / David C Swinney
  • ITC: More Than Just Binding Affinities / Ernesto Freire
  • Index.
  • The revolution of real-time, label-free biosensor applications / Rebecca L. Rich and David G. Myszka
  • Design and implementation of vertically emitting distributed feedback lasers for biological sensing / Meng Lu [and others]
  • SPR screening of chemical microarrays for fragment based discovery / Thomas Neumann and Renate Sekul
  • The cellkey system : a label-free cell-based assay platform for early drug discovery applications / Ryan P. McGuinness [and others]
  • Dynamic and label-free cell-based assays using the xcelligence system / Yama A. Abassi [and others]
  • Selecting the best HTS hits to move forward : ITC ligand binding characterization provides guidance / Ronan O'Brien & Richard Brown
  • Incorporating transmitted light modalities into high-content analysis assays / Robert Graves
  • Nonradioactive rubidium efflux assay technology for screening of ion channels / Georg C. Terstappen
  • Expanding the scope of HTMS methods / Tom G. Holt [and others]
  • A novel multiplex SPR array for rapid screening and affinity determination of monoclonal antibodies : the proteon XPR36 label free system : kinetic screening of monoclonal antibodies / Vered Bronner, Oded Nahshol, and Tsafrir Bravman
  • Biophysics/label-free assays in hit discovery and verification / Johannes Ottl
  • Harnessing optical label-free on microtiter plates for lead finding from binding to phenotypes / Julio Martin
  • Use of label-free detection technologies in the hit-to-lead process: surface optical detection of cellular processes / F. Stuhmeier [and others]
  • Cellular screening for 7TMS using label-free detection / Jeffrey C. Jerman, Jason Brown, and Magalie Rocheville
  • Novartis evaluation of the ForteBio Octet RED : a versatile instrument for direct-binding experiments / Eric Martin [and others]
  • The pyramid approach to fragment-based biophysical screening / Glyn Williams
  • Characterisation of antibodies against the active conformation of Gài1 using the SRU-BIND label free detection system / Melanie Leveridge, Chun-Wa Chung, and Trevor Wattam
  • SPR based direct binding assays in drug discovery / Walter Huber
  • Kinetic binding mechanisms: their contribution to an optimal therapeutic index / David C. Swinney
  • ITC : more than just binding affinities / Ernesto Freire.

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