Protein kinases as drug targets /
With Kinase inhibitors being widely seen as the long-sought 'magic bullet' to conquer cancer, this fully comprehensive guide to kinase inhibitor drug development covers the entire drug pipeline from target identification to compound development and clinical application. Volume 1 focuses up...
| Συγγραφή απο Οργανισμό/Αρχή: | |
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| Άλλοι συγγραφείς: | , |
| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Weinheim :
Wiley-VCH ;
[2011]
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| Σειρά: | Methods and principles in medicinal chemistry ;
49. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
| Περίληψη: | With Kinase inhibitors being widely seen as the long-sought 'magic bullet' to conquer cancer, this fully comprehensive guide to kinase inhibitor drug development covers the entire drug pipeline from target identification to compound development and clinical application. Volume 1 focuses upon the medicinal chemistry of kinase drugs, from target identification to lead optimization, and contains numerous contributions from large and small pharmaceutical companies. Volume 2 surveys current and future therapeutic application areas for kinase inhibitor drugs, with a strong focus on oncology drugs, as this is the most important therapeutic field for these drugs. In addition, all six currently approved kinase inhibitor drugs (small molecules and antibodies) are described, and their performances in clinical practice are discussed. |
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| Φυσική περιγραφή: | 1 online resource (xxi, 373 pages) : illustrations (some color). |
| Βιβλιογραφία: | Includes bibliographical references and index. |
| ISBN: | 9783527633470 3527633472 9783527633487 3527633480 1283283247 9781283283243 |
| DOI: | 10.1002/9783527633470 |
