Biothermodynamics. Part D /

• Other Authors: Johnson, Michael L., 1947-, Holt, Jo M., Ackers, Gary K.
• Format: eBook
• Language: English
• Published: Amsterdam, Netherlands ; Boston, Mass. : Elsevier/Academic Press, ©2011.
• Series: Methods in enzymology ; v. 492.
• Subjects: Thermodynamics.; Protein binding.; Protein-protein interactions.; Ligands (Biochemistry); SCIENCE > Life Sciences > Biochemistry.; Protein Binding.; Protein Array Analysis.; Ligands.; Electronic books.
• Physical Description: 1 online resource (xliii, 323 pages, [8] pages of plates) : illustrations (some color).
• Bibliography: Includes bibliographical references and indexes.
• ISBN: 9780123860040; 0123860040; 9780123860033; 0123860032
• ISSN: 0076-6879 ;

The use of thermodynamics in biological research can be equated to an energy book-keeping system. While the structure and function of a molecule is important, it is equally important to know what drives the energy force. This volume presents sophisticated methods for estimating the thermodynamic parameters of specific protein-protein, protein-DNA and small molecule interactions. * Elucidates the relationships between structure and energetics and their applications to molecular design, aiding researchers in the design of medically important molecules * Provides a "must-have" methods volume that keeps MIE buyers and online subscribers up-to-date with the latest research * Offers step-by-step lab instructions, including necessary equipment, from a global research community.