Carbohydrate Recognition : Biological Problems, Methods, and Applications /

• Άλλοι συγγραφείς: Wang, Binghe, 1962-, Boons, Geert-Jan
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : Wiley, [2011]
• Σειρά: Wiley series in drug discovery and development.
• Θέματα: Carbohydrates > Therapeutic use.; Carbohydrates > physiology.; Carbohydrates > therapeutic use.; Lectins.; Protein Binding.; MEDICAL > Biochemistry.; Electronic books.; Electronic resource.

 "This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic and diagnostic agents. The book covers (1) biological problems involving carbohydrate recognition, (2) structural factors mediating carbohydrate recognition, (3) design and synthesis of lectin mimics that recognize carbohydrate ligands with high specificity and affinity, and (4) modulation of biological and pathological processes through carbohydrate recognition"--Provided by publisher. 

 Frontmatter -- Color Plates -- Mammalian Glycan Biosynthesis: Building a Template for Biological Recognition / M Adam Meledeo, Venkata D P Paruchuri, Jian Du, Zhiyun Wang, Kevin J Yarema -- The Roles of Carbohydrate Binding in Cell Adhesion and Inflammation / Ken Kitajima, Chihiro Sato -- The Role of Carbohydrates in Viral Infections / Gillian M Air -- The Role of Carbohydrates in Bacterial Infections / Roland J Pieters -- The Roles of Carbohydrate Binding in Fertilization / David J Miller -- Carbohydrate Biomarkers / Yunfeng Cheng, Nanting Ni, Hanjing Peng, Shan Jin, Binghe Wang -- Galectins and their Role in Various Biological Processes / Sarika Saraswati, Ashley Stanley Block, Alan B Diekman -- Glycoimmunology / Ani Grigorian, Barbara Newton, Michael Demetriou -- Tools for Glycomics: Glycan and Lectin Microarrays / Christopher Campbell, Jeff Gildersleeve -- Combinatorial Biosynthesis of Complex Carbohydrates / Hai Yu, Xi Chen -- Mass Spectrometry in Carbohydrate Sequencing and Binding Analysis / Gregory O Staples, Joseph Zaia -- Synthetic Lectin Mimics Artificial Carbohydrate Receptors / Xiaochuan Yang, Yunfeng Cheng, Binghe Wang -- Lectin Binding and its Structural Basis / Annabelle Varrot, Bertrand Blanchard, Anne Imberty -- Multivalency in Carbohydrate Binding / Mark L Wolfenden, Mary J Cloninger -- Carbohydrate Binding Agents: Potential Therapeutics with Multiple Inhibitory Actions against Enveloped Viruses / K O Fraṅois, J Balzarini -- Informatics for Glycobiology and Glycomics / Kiyoko F Aoki-Kinoshita -- Index.