Oral Bioavailability : Basic Principles, Advanced Concepts, and Applications /
Understand and assess the design, delivery, and efficacy of orally administered drugs A practical guide to understanding oral bioavailability, one of the major hurdles in drug development and delivery, Oral Bioavailability: Basic Principles, Advanced Concepts, and Applications is designed to help ch...
| Άλλοι συγγραφείς: | , |
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| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Hoboken, N.J. :
John Wiley & Sons,
[2011]
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| Σειρά: | Wiley series in drug discovery and development.
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| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Frontmatter
- Color Plates
- Barriers to Oral Bioavailability--An Overview / Ming Hu, Xiaoling Li
- Physicochemical Characterization of Pharmaceutical Solids / Smita Debnath
- Solubility of Pharmaceutical Solids / Lauren Wiser, Xiaoling Gao, Bhaskara Jasti, Xiaoling Li
- Dissolution of Pharmaceutical Solids / Josephine L P Soh, Paul W S Heng
- Biological and Physiological Features of the Gastrointestinal Tract Relevant to Oral Drug Absorption / Paul C Ho
- Absorption of Drugs via Passive Diffusion and Carrier-Mediated Pathways / Miki Susanto Park, Jae H Chang
- Correlations of Pharmaceutical Dosage Forms / Deliang Zhou, Yihong Qiu
- Drug Metabolism in Gastrointestinal Tract / Rashim Singh, Ming Hu
- Efflux of Drugs via Transporters--The Antiabsorption Pathway / Jae H Chang, James A Uchizono, Miki Susanto Park
- Liver Drug Metabolism / Leslie M Tompkins, Hongbing Wang
- Protein Binding of Drugs / Antonia Kotsiou, Christine Tesseromatis
- Urinary Excretion of Drugs and Drug Reabsorption / Pankaj Gupta, Bo Feng, Jack Cook
- Pharmacokinetic Behaviors of Orally Administered Drugs / Jaime A Yez, Dion R Brocks, Laird M Forrest, Neal M Davies
- Effects of Food on Drug Absorption / Venugopal P Marasanapalle, Xiaoling Li, Bhaskara R Jasti
- Drug₆Drug Interactions and Drug-Dietary Chemical Interactions / Ge Lin, Zhong Zuo, Na Li, Li Zhang
- Anatomical and Physiological Factors Affecting Oral Drug Bioavailability in Rats, Dogs, and Humans / Ayman El-Kattan, Susan Hurst, Joanne Brodfuehrer, Cho-Ming Loi
- Amino Acid Drug Transporters / Zhong Qiu, Ming Hu
- Drug Transporters and Their Role in Absorption and Disposition of Peptides and Peptide-Based Pharmaceuticals / David J Lindley, Stephen M Carl, Dea Herrera-Ruiz, Li F Pan, Lori B Karpes, Jonathan M E Goole, Olafur S Gudmundsson, Gregory T Knipp
- Organic Anion and Cation Drug Transporters / Takashi Sekine, Hiroyuki Kusuhara
- Gastric Retentive Drug Delivery Systems / John R Cardinal, Avinash Nangia
- Lipid-Based and Self-Emulsifying Oral Drug Delivery Systems / Sravan Penchala, Anh-Nhan Pham, Ying Huang, Jeffrey Wang
- Prodrug Strategies to Enhance Oral Drug Absorption / Sai H S Boddu, Deep Kwatra, Ashim K Mitra
- Oral Delivery of Protein/Peptide Therapeutics / Puchun Liu, Steven Dinh
- ABC Transporters in Intestinal and Liver Efflux / Marilyn E Morris, Yash A Gandhi
- Interplay between Efflux Transporters and Metabolic Enzymes / Stephen Wang
- Regulatory Considerations in Metabolism- and Transporter-Based Drug Interactions / Yuanchao (Derek) Zhang, Lei Zhang, John M Strong, Shiew-Mei Huang
- Caco-2 Cell Culture Model for Oral Drug Absorption / Kaustubh Kulkarni, Ming Hu
- MDCK Cells and Other Cell-Culture Models of Oral Drug Absorption / Deep Kwatra, Sai H S Boddu, Ashim K Mitra
- Intestinal Perfusion Methods for Oral Drug Absorptions / Wei Zhu, Eun Ju Jeong
- Liver Perfusion and Primary Hepatocytes for Studying Drug Metabolism and Metabolite Excretion / Cindy Q Xia, Chuang Lu, Suresh K Balani
- Methods for Oral Bioavailability Studies / Ana Ruiz-Garcia, Marival Bermejo
- Determination of Regulation of Drug-Metabolizing Enzymes and Transporters / Bin Zhang, Wen Xie
- Computational and Pharmacoinformatic Approaches to Oral Bioavailability Prediction / Miguel Angel Cabrera-P̌rez, Isabel Gonzalez-alvarez
- Index
- Wiley Series in Drug Discovery and Development.
