Platelet proteomics : principles, analysis, and applications /

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential appli...

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Bibliographic Details
Corporate Author: Wiley InterScience (Online service)
Other Authors: García, Ángel, 1968-, Senis, Yotis A., 1970-
Format: eBook
Language:English
Published: Hoboken, N.J. : John Wiley & Sons, [2011]
Series:Wiley-Interscience series on mass spectrometry.
Subjects:
Online Access:Full Text via HEAL-Link
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049 |a MAIN 
245 0 0 |a Platelet proteomics :  |b principles, analysis, and applications /  |c edited by Ángel García, Yotis A. Senis. 
264 1 |a Hoboken, N.J. :  |b John Wiley & Sons,  |c [2011] 
264 4 |c ©2011 
300 |a 1 online resource (xx, 403 pages) :  |b illustrations. 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
490 1 |a Wiley-Interscience series on mass spectrometry 
504 |a Includes bibliographical references and index. 
505 0 |a Platelets and their role in thrombotic and cardiovascular disease : the impact of proteomic analysis / by Ronald Stanley & Jon Gibbins -- Mass spectrometry-based proteomics : general overview, and PTMS analysis in the context of platelet research / by Julia Burkhart & Albert Sickmann -- Sample preparation variables in platelet proteomics for biomarker research / by Maria Zellner and Rudolf Oehler -- Two-dimensional gel electrophoresis : basic principles and application to platelet signaling studies / by Ángel García -- The platelet membrane proteome / by Yotis A. Senis -- Organellar proteomics and the analysis of the platelet releasate / by James McRedmond -- The platelet microparticle proteome / by David Smalley -- N-terminal cofradic analysis of the human platelet proteome / by Kris Gevaert et al. -- Sage to study the platelet and megakaryocyte transcriptome / by Mike Tomlinson -- The application of microarray analysis and its integration with proteomics to study platelet-associated disorders / by Wadie Bahou and Dimitri Gnatenko -- Platelet functional genomics / by Isabelle I. Salles et al. -- The systems biology to study platelet-related bleeding disorders / by Jan Willem Akkerman and Bernard de Bono -- Platelet proteomics in transfusion medicine / by Andreas Greinacher & Thomas Thiele -- Cardiovascular proteomics / by Fernando Vivanco et al. 
588 0 |a Print version record. 
520 |a The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics. This chapter shows potential applications for platelet proteomics not yet carried out. It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research done so far on platelet proteomics. This includes general proteome mapping by non-gel based separat. 
650 0 |a Blood platelets. 
650 0 |a Proteomics. 
650 4 |a Physiology. 
650 4 |a Science. 
650 4 |a Natural history. 
650 7 |a MEDICAL  |x Physiology.  |2 bisacsh 
650 7 |a SCIENCE  |x Life Sciences  |x Human Anatomy & Physiology.  |2 bisacsh 
650 7 |a Blood platelets.  |2 fast  |0 (OCoLC)fst00834782 
650 7 |a Proteomics.  |2 fast  |0 (OCoLC)fst01079785 
650 2 |a Blood Platelets  |x physiology. 
650 2 |a Cardiovascular Diseases  |x physiopathology. 
650 2 |a Proteomics  |x methods. 
650 2 |a Thrombosis  |x physiopathology. 
655 4 |a Electronic books. 
655 7 |a Electronic books.  |2 local 
700 1 |a García, Ángel,  |d 1968- 
700 1 |a Senis, Yotis A.,  |d 1970- 
710 2 |a Wiley InterScience (Online service) 
776 0 8 |i Print version:  |t Platelet proteomics.  |d Hoboken, N.J. : John Wiley & Sons, ©2011  |w (OCoLC)730519654 
830 0 |a Wiley-Interscience series on mass spectrometry. 
856 4 0 |u https://doi.org/10.1002/9780470940297  |z Full Text via HEAL-Link 
994 |a 92  |b DG1