Chiral drugs : chemistry and biological action /

• Άλλοι συγγραφείς: Lin, Guo-Qiang, 1943-, You, Qi-Dong, Cheng, Jie-Fei
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : Wiley, [2011]
• Θέματα: Chiral drugs.; Drug development.; Structure-activity relationships (Biochemistry); Drug Discovery > methods.; Pharmaceutical Preparations > chemistry.; Structure-Activity Relationship.; MEDICAL > Drug Guides.; MEDICAL > Nursing > Pharmacology.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; Electronic books.

"This book overviews chiral drugs and their impact in the pharmaceutical industry. The chapters detail basics and trends in chiral drug discovery and development, as well as techniques / skills and trends of asymmetric synthesis. The first section introduces the general concept of chirality and...

Πίνακας περιεχομένων:

• Overview of chirality and chiral drugs / Guo-Qiang Lin, Jiange Zhang and Jie-Fei Cheng
• Chiral drugs through asymmetric synthesis / Guo-Quiang Lin and Xing-Wen Sun
• Chiral drugs via biocatalytical approaches / Jianqiang Wang and Wenya Lu
• Chiral resolution / Qi-Dong You
• Fluorine-containing chiral drugs / Xiao-Long Qiu, Xuyi Yue and Feng-Ling Qing
• Industrial application of chiral technologies / Hui-Ying (Harry) Li, Rui Liu, Carl Behrens, and Chao-Ying Ni
• Computation modeling study on mechanism-of-action of chiral drugs / Deping Wang and Eric Gu
• Pharmacology of chiral drugs / Yongge Liu and Xiao-Hui Gu
• Pharmacokinetics of chiral drugs / Hanqing Dong, Xiaochuan Guo and Zengbiao Li
• 10. Toxicology of chiral drugs / Guang Yang and Hai-Zhi Bu
• Representative chiral drugs / Jiangqin Sun, Dingguo Liu and Zhimin Wang.