HIV-1 integrase : mechanism and inhibitor design /

• Other Authors: Neamati, Nouri (Editor)
• Format: eBook
• Language: English
• Published: Hoboken, N.J. : Wiley, [2011]
• Series: Wiley series in drug discovery and development.
• Subjects: HIV (Viruses) > Enzymes.; HIV (Viruses) > Enzymes > Inhibitors.; Antiviral agents.; HIV Integrase Inhibitors > pharmacology.; Drug Design.; HIV Integrase.; HEALTH & FITNESS > Diseases > AIDS & HIV.; MEDICAL > AIDS & HIV.; Electronic books.
• Physical Description: 1 online resource (xiii, 506 pages, [16] pages of plates) : illustrations (some color).
• Bibliography: Includes bibliographical references and index.
• ISBN: 9781118015377; 1118015371; 9781118015353; 1118015355
• DOI: 10.1002/9781118015377

This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and researchers in antiviral drug discovery. Despite numerous review articles and isolated book chapters dealing with HIV-1 integrase, there has not been a single source for those working to devise anti-AIDS drugs against this promising target. But this book fills that gap and offers a valuable introduction to the field for the interdisciplinary scientists who will need to work together to design drugs that target HIV-1.