Advanced therapy for hepatitis C /

• Άλλοι συγγραφείς: McCaughan, Geoffrey W., McHutchison, J. G., Pawlotsky, Jean-Michel
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Chichester, West Sussex : Blackwell, 2012.
• Θέματα: Hepatitis C > Treatment.; Antiviral agents.; Hepatitis C > therapy.; Antiviral Agents > therapeutic use.; MEDICAL > Hepatology.; Electronic books.

 Hepatologists, both researchers and front-line clinicians, now have a comprehensive guide to the treatment of patients with the HCV virus. This book focuses mainly on the efficacy and clinical use of antiviral therapies, including the use of antivirals post liver transplantation and in the presence of the HIV virus. It also explores the foundations for understanding antiviral therapies in HCV, such as the complex pharmacology and mechanisms of antiviral drugs. A 'late-breaking information' chapter contains the most recent trial results on the latest antiviral drugs. 

 HCV replication / Michael R. Beard -- Hepatitis C virus genotypes / Scott A. Read and Mark W. Douglas -- Immune responses to HCV : implications for therapy / David G Bowen -- Mechanisms of action of antiviral drugs : the interferons / Edmund Tse and Michael R Beard -- Pharmacology and mechanisms of action of antibviral drugs : ribavarin analogues / Fred Poordad and Grace M. Chee -- Pharmacology and mechanisms of action of antiviral drugs : polymerase inhibitors / Lotte Coelmont [and others] -- Pharmacology and mechanisms of action of antiviral drugs : protease inhibitors / Laurent Chatel-Chaix, Martin Baril, and Daniel Lamarre -- Measuring antiviral responses / Jean-Michel Pawlotsky and Stéphane Chevaliez -- Genotype 1 : standard treatment / Rebekah G. Gross and Ira M. Jacobson -- Individually tailored treatment strategies in treatment naïve chronic hepatitis C genotype 1 patients / Johannes Wiegand and Thomas Berg -- Genotype 1 relapsers and nonresponders / Salvatore Petta and Antonio Craxì -- Standard therapy for genotype 2/3 / Kenneth Yan and Amany Zekry -- Altered dosage or durations of current antiviral therapy for HCV genotype 2 and 3 / Alessandra Mangia, Leonardo Mottola, Angelo Andriulli -- Genotype 2/3 relapse and non response / Stella Martínez, Jose Maŕia Sánchez-Tapias, and Xavier Forns -- Hepatitis C genotype 4 therapy: progress and challenges / Sanaa M. Kamal -- Antivirals in acute hepatitis C / Heiner Wedemeyer -- Antivirals in cirrhosis and portal hypertension / Diarmuid S. Manning and Nezam H. Afdhal -- Treatment of recurrent hepatitis C following liver transplantation / Ed Gane -- Antiviral treatment in chronic hepatitis C virus infection with extra hepatic manifestations / Benjamin Terrier and Patrice Cacoub -- Cytopenias : how they limit therapy and potential correction / Mitchell L. Shiffman -- The problem of insulin resistance and its effect on therapy / Venessa Pattullo and Jacob George -- HIV and hepatitis C co-infection / Gail V. Matthews and Gregory J. Dore -- HCV and racial differences / Andrew J. Muir -- HCV and the pediatric population / Kathleen B. Schwarz -- New horizons : il28; direct-acting antiviral therapy for HCV -- Alexander J. Thompson, John G. Mchutchison, Geoff W. Mccaughan.