Proteomics of biological systems : protein phosphorylation using Mass spectrometry techniques /

• Main Author: Ham, Bryan M.
• Corporate Author: Wiley InterScience (Online service)
• Format: eBook
• Language: English
• Published: Hoboken, N.J. : John Wiley & Sons, [2012]
• Subjects: Proteomics > Methodology.; Phosphorylation > Research > Methodology.; Phosphoproteins > Synthesis.; Mass spectrometry.; SCIENCE > Life Sciences > Biochemistry.; Science.; Electronic resource.; Electronic books.

Phosphorylation is the addition of a phosphate (PO₄) group to a protein or other organic molecule. Phosphorylation activates or deactivates many protein enzymes, causing or preventing the mechanisms of diseases such as cancer and diabetes. This book shows how to use mass spectrometry to determine wh...

Table of Contents:

• Posttranslational Modification (PTM) of Proteins
• Glycosylation of Proteins
• Sulfation of Proteins as Posttranslational Modification
• Eukaryote PTM as Phosphorylation: Normal State Studies
• Eukaryote PTM as Phosphorylation: Perturbed State Studies
• Prokaryotic Phosphorylation of Serine, Threonine, and Tyrosine
• Prokaryotic Phosphorylation of Histidine
• Appendix I: Atomic Weights and Isotopic Compositions
• Appendix II: Periodic Table of the Elements
• Appendix III: Fundamental Physical Constants.