Protein engineering for therapeutics. Part B /

• Άλλοι συγγραφείς: Wittrup, K. Dane (Επιμελητής έκδοσης), Verdine, Gregory L. (Gregory Lawrence) (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego, Calif. : Academic, 2012.
• Έκδοση: 1st ed.
• Σειρά: Methods in enzymology ; v. 503.
• Θέματα: Proteins > Therapeutic use.; Protein engineering.; Electronic books.

This volume of Methods in Enzymology looks at Protein Engineering for Therapeutics. The chapters provide an invaluable resource for academics, researchers and students alike. With an international board of authors, this volume is split into sections that cover subjects such as Peptides, and Scaffold...

Πίνακας περιεχομένων:

• Part III: Peptides Stapled Peptides for Intracellular Drug Targets Mapping of vascular zip codes by phage display Engineering cyclic peptide toxins Peptide Discovery using Bacterial Display and Flow Cytometry Part V: Scaffolds Designed Ankyrin Repeat Proteins (DARPins): From research to therapy Target-binding proteins based on the tenth human fibronectin type III domain (10Fn3) Anticalins: small engineered binding proteins based on the lipocalin scaffold T Cell Receptor Engineering Engineering Knottins as Novel Binding Agents
• Part VI: Pharmacokinetics Practical Theoretic Guidance for the Design of Tumor Targeting Agents Re-Engineering Biopharmaceuticals for Targeted Delivery Across the Blood-Brain Barrier Engineering and Identifying Supercharged Proteins for Macromolecule Delivery into Mammalian Cells.