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04676nam a2200697 4500 |
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ocn785722063 |
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OCoLC |
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20170124072110.1 |
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m o d |
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cr un|---uuuuu |
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120411s2012 enk ob 001 0 eng |
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|a 2012015088
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|a DLC
|b eng
|e pn
|c DLC
|d YDX
|d EBLCP
|d N$T
|d UIU
|d MERUC
|d DG1
|d YDXCP
|d E7B
|d UBY
|d UWO
|d CDX
|d DEBSZ
|d IUL
|d OCLCF
|d COO
|d OCLCQ
|d GrThAP
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|a 811865406
|a 844915169
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|a 9781118348994
|q (ePub)
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|a 1118348990
|q (ePub)
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|a 9781118348963
|q (Adobe PDF)
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|a 1118348966
|q (Adobe PDF)
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|a 9781118348987
|q (MobiPocket)
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|a 1118348982
|q (MobiPocket)
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|a 9781118348970
|q (electronic bk.)
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|a 1118348974
|q (electronic bk.)
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|z 9781119995951
|q (cloth)
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|z 1119995957
|q (cloth)
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|z 9781119995944
|q (pbk.)
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|z 1119995949
|q (pbk.)
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|a AU@
|b 000049032391
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|a AU@
|b 000059227966
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|a (OCoLC)785722063
|z (OCoLC)811865406
|z (OCoLC)844915169
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|a pcc
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0 |
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|a QP601
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|a MED
|x 008000
|2 bisacsh
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0 |
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|a 612/.0151
|2 23
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|a MAIN
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|a Bugg, Tim.
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245 |
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|a Introduction to enzyme and coenzyme chemistry /
|c T.D.H. Bugg.
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250 |
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|a 3rd ed.
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264 |
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|a Chichester, West Sussex :
|b Wiley,
|c 2012.
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300 |
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|a 1 online resource.
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336 |
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|a text
|b txt
|2 rdacontent
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|a computer
|b c
|2 rdamedia
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|a online resource
|b cr
|2 rdacarrier
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|a Includes bibliographical references and index.
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|a Print version record and CIP data provided by publisher.
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|a 2.6 The folded tertiary structure of proteins2.7 Enzyme structure and function; 2.8 Metallo-enzymes; 2.9 Membrane-associated enzymes; 2.10 Glycoproteins; 3 Enzymes Are Wonderful Catalysts; 3.1 Introduction; 3.2 A thermodynamic model of catalysis; 3.3 Proximity effects; 3.4 The importance of transition state stabilisation; 3.5 Acid/base catalysis in enzymatic reactions; 3.6 Nucleophilic catalysis in enzymatic reactions; 3.7 The use of strain energy in enzyme catalysis; 3.8 Desolvation of substrate and active site nucleophiles; 3.9 Catalytic perfection.
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|a 3.10 The involvement of protein dynamics in enzyme catalysis4 Methods for Studying Enzymatic Reactions; 4.1 Introduction; 4.2 Enzyme purification; 4.3 Enzyme kinetics; 4.4 The stereochemical course of an enzymatic reaction; 4.5 The existence of intermediates in enzymatic reactions; Direct observation; Trapping; Chemical inference; Isotope exchange; 4.6 Analysis of transition states in enzymatic reactions; 4.7 Determination of active site catalytic groups; 5 Hydrolytic and Group Transfer Enzymes; 5.1 Introduction; 5.2 The peptidases; The Serine Proteases; The Cysteine Proteases.
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|a The Metallo-proteasesThe Aspartyl Proteases; CASE STUDY: HIV-1 protease; 5.3 Esterases and lipases; 5.4 Acyl transfer reactions in biosynthesis (coenzyme A); 5.5 Enzymatic phosphoryl transfer reactions; 5.6 Adenosine 5'-triphosphate (ATP); 5.7 Enzymatic glycosyl transfer reactions; 5.8 Methyl group transfer: use of S-adenosyl methionine and tetrahydrofolate coenzymes for one-carbon transfers; 6 Enzymatic Redox Chemistry; 6.1 Introduction; 6.2 Nicotinamide adenine dinucleotide-dependent dehydrogenases; 6.3 Flavin-dependent dehydrogenases and oxidases; 6.4 Flavin-dependent mono-oxygenases.
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|a Looking at enzymes from an organic chemistry perspective, this updated reference includes information on recent advances in our understanding of enzyme action; topical examples to illustrate key points; two-color figures of the active sites of enzymes discussed in the text to illustrate the interplay between enzyme structure and function; and end-of-chapter problems to allow readers to check their understanding of the material. This concise but comprehensive guide is essential for undergraduate and postgraduate students of organic, bio-organic, and medicinal chemistry, chemical biology, bioche.
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650 |
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|a Enzymes.
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650 |
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|a Coenzymes.
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650 |
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|a MEDICAL
|x Biochemistry.
|2 bisacsh
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650 |
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7 |
|a Coenzymes.
|2 fast
|0 (OCoLC)fst00866295
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650 |
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|a Enzymes.
|2 fast
|0 (OCoLC)fst00913605
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655 |
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|a Electronic books.
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776 |
0 |
8 |
|i Print version:
|a Bugg, Tim.
|t Introduction to enzyme and coenzyme chemistry.
|b 3rd ed.
|d Hoboken, NJ : Wiley, 2012
|z 9781119995951
|w (DLC) 2012008853
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856 |
4 |
0 |
|u https://doi.org/10.1002/9781118348970
|z Full Text via HEAL-Link
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|a 92
|b DG1
|