Plant Bioactives and Drug Discovery : Principles, Practice, and Perspectives /

• Άλλοι συγγραφείς: Cechinel-Filho, Valdir
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : John Wiley & Sons, [2012]
• Σειρά: Wiley series in drug discovery and development.
• Θέματα: Materia medica, Vegetable.; Plant bioactive compounds.; Medicinal plants.; Drug development.; Plant extracts.; Pharmaceutical chemistry.; Plants, Medicinal > metabolism.; Drug Discovery.; Plant Extracts > pharmacology.; HEALTH & FITNESS > Herbal Medications.; Electronic books.

 "An in-depth exploration of the applications of plant bioactive metabolites in drug research and development. Highlighting the complexity and applications of plant bioactive metabolites in organic and medicinal chemistry, Plant Bioactives and Drug Discovery: Principles, Practice, and Perspectives provides an in-depth overview of the ways in which plants can inform drug research and development. An edited volume featuring multidisciplinary international contributions from acclaimed scientists researching bioactive natural products, the book provides an incisive overview of one of the most important topics in pharmaceutical studies today. With coverage of strategic methods of natural compound isolation, structural manipulation, natural products in clinical trials, quality control, and more, and featuring case studies on medicinal plants, the book serves as a definitive guide to the field of plant biodiversity as it relates to medicine. In addition, chapters on using natural products as drugs that target specific disease areas, including neurological disorders, inflammation, infectious diseases, and cancer, illustrate the myriad possibilities for therapeutic applications. Wide ranging and comprehensive, Plant Bioactives and Drug Discovery also includes important information on marketing, regulations, intellectual property rights, and academic-industry collaboration as they relate to plant-based drug research, making it an essential resource for advanced students and academic and industry professionals working in biochemical, pharmaceutical, and related fields."--   Provided by publisher. 

 Natural products in drug discovery : recent advances / Gordon M. Cragg, Paul G. Grothaus, David J. Newman -- Modern approaches in the search for new active compounds from crude extracts of natural sources / Emerson F. Queiroz, Kurt Hostettmann, Jean-Luc Wolfender -- Natural products as lead compounds in medicinal chemistry / Eliezer J. Barreiro, Carlos A.M. Fraga and Lidia M. Lima -- The importance of structural manipulation of natural compounds in drug discovery and development / Arturo San Feliciano [and others] -- The action of plants and their constituents on the central nervous system / Fulvio R. Mendes [and others] -- The role of natural products in discovery of new anti-infective agents with emphasis on antifungal compounds / Maximiliano Sortino [and others] -- Antiulcer agents from higher plants / Luiz C. Klein-Junior, José R. Santin and Sérgio F. de Andrade -- Recent progress in the chemistry and biology of paclitaxel (Taxol) and related taxanes / Jun Qi, Jielu Zhao and David G.I. Kingston -- Cancer chemopreventive activity of higher plants / A. Douglas Kinghorn [and others] -- Medicinal plants and pharmaceutical technology / Ruth M. Lucinda da Silva, Angélica G. Couto and Tania M.B. Bresolin -- Natural products in clinical trials / Sigrun Chrubasik -- The influence of biotic and abiotic factors on the production of secondary metabolites in medicinal plants / Dayana R. Gouveia, Leonardo Gobbo-Neto and Norberto P. Lopes -- Production of bioactives compounds : the importance of Pictet-Spengler reaction in the XXI century / Pilar Menendez [and others] -- Screening methods for drug discovery from plants / Alan L. Harvey -- Phytotherapeutics: intellectual property rights, global market, and global regulatory guidelines / James D. McChesney, Raymond Cooper and Kip Vought -- Cooperation between the pharmaceutical industry and academic institutions in drug discovery / Valdir Cechinel Filho, Rivaldo Niero, and Rosendo A. Yunes.