Protein-ligand interactions /
Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key expe...
| Other Authors: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Weinheim :
Wiley-VCH,
[2012]
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| Series: | Methods and principles in medicinal chemistry ;
v. 53. |
| Subjects: | |
| Online Access: | Full Text via HEAL-Link |
| Summary: | Innovative and forward-looking, this volume focuses on recent achievements in this rapidly progressing field and looks at future potential for development. The first part provides a basic understanding of the factors governing protein-ligand interaction, followed by a comparison of the four key experimental methods (calorimetry, surface plasmon resonance, NMR and X-ray crystallography) used in generating interaction data. The second half of the book is devoted to in-silico methods of modeling and predicting molecular recognition and binding. Here, as elsewhere in the book, emphasis is placed on novel approaches and recent improvements to established methods. The final part looks at unresolved challenges, and the strategies to address them. |
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| Physical Description: | 1 online resource (xx, 339 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783527645978 3527645977 3527329668 9783527329663 9781280662898 1280662891 |
| DOI: | 10.1002/9783527645947 |
