Telomerases : chemistry, biology and clinical applications /

"This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis,...

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Bibliographic Details
Other Authors: Lue, Neal F., 1962-, Autexier, Chantal, 1963-
Format: eBook
Language:English
Published: Hoboken : John Wiley & Sons, 2012.
Subjects:
Online Access:Full Text via HEAL-Link
Description
Summary:"This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher.
Physical Description:1 online resource (x, [16], 308 pages) : illustrations (some color)
Bibliography:Includes bibliographical references and index.
ISBN:9781118268667
1118268660
9781118268506
1118268504
9781280768736
1280768738
9781118267516
1118267516
DOI:10.1002/9781118268667