Telomerases : chemistry, biology and clinical applications /

"This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis,...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Lue, Neal F., 1962-, Autexier, Chantal, 1963-
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Hoboken : John Wiley & Sons, 2012.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
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049 |a MAIN 
245 0 0 |a Telomerases :  |b chemistry, biology and clinical applications /  |c edited by Neal F. Lue and Chantal Autexier. 
264 1 |a Hoboken :  |b John Wiley & Sons,  |c 2012. 
300 |a 1 online resource (x, [16], 308 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent 
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380 |a Bibliography 
520 |a "This book is a comprehensive and up-to-date review and evaluation of the contemporary status of telomerase research. Chapters in this volume cover the basic structure, mechanisms, and diversity of the essential and regulatory subunits of telomerase. Other topics include telomerase biogenesis, transcriptional and post-translational regulation, off-telomere functions of telomerase and the role of telomerase in cellular senescence, aging and cancer. Its relationship to retrotransposons, a class of mobile genetic elements that shares similarities with telomerase and serves as telomeres in selected organisms, are also reviewed"--Provided by publisher. 
588 0 |a Print version record. 
505 0 |a The telomerase complex : an overview / Johanna Mancini and Chantal Autexier -- Telomerase RNA : structure, function, and molecular mechanisms / Yehudi Tzfati and Julian J.-L. Chen -- TERT structure, function, and molecular mechanisms / Emmanuel Skordalakes and Neal F. Lue -- Telomerase biogenesis : RNA Processing, trafficking and protein Interactions / Tara Beattie and Pascal Chartrand -- Transcriptional regulation of human telomerase / Antonella Farsetti and Yu-Sheng Cong -- Telomerase regulation and telomere length homeostasis / Joachim Lingner and David Shore -- Telomere structure in telomerase regulation / Momchil D. Vodenicharov and Raymund J. Wellinger -- Off-telomere functions of telomerase / Kenkichi Masutomi and William C. Hahn -- Murine Models of Dysfunctional Telomeres and Telomerase / Yie Liu and Lea Harrington -- Cellular senescence, telomerase, and cancer in human cells / Phillip G. Smiraldo [and others] -- Telomerase, retrotransposons, and evolution / Irina R. Arkhipova. 
504 |a Includes bibliographical references and index. 
650 0 |a Telomerase  |x Physiology. 
650 0 |a Telomerase  |x Metabolism. 
650 0 |a Telomerase  |x Genetics. 
650 0 |a Geriatrics. 
650 4 |a Natural history. 
650 4 |a Science. 
650 7 |a SCIENCE  |x Life Sciences  |x Molecular Biology.  |2 bisacsh 
650 7 |a SCIENCE  |x Life Sciences  |x Genetics & Genomics.  |2 bisacsh 
650 7 |a Science.  |2 fast  |0 (OCoLC)fst01108176 
650 1 2 |a Telomerase. 
655 4 |a Electronic books. 
655 7 |a Electronic books.  |2 local 
700 1 |a Lue, Neal F.,  |d 1962- 
700 1 |a Autexier, Chantal,  |d 1963- 
776 0 8 |i Print version:  |a Lue, Neal.  |t Telomerases : Chemistry, Biology and Clinical Applications.  |d Hoboken : John Wiley & Sons, ©2012  |z 9780470592045 
856 4 0 |u https://doi.org/10.1002/9781118268667  |z Full Text via HEAL-Link 
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