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03967nam a2200769 4500 |
| 001 |
ocn794619804 |
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OCoLC |
| 005 |
20170124071837.2 |
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m o d |
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110510s2011 nju ob 001 0 eng d |
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|z 2011019939
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| 049 |
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|a MAIN
|
| 100 |
1 |
|
|a Peters, Sheila Annie.
|
| 245 |
1 |
0 |
|a Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulations :
|b Principles, Methods, and Applications in the Pharmaceutical Industry /
|c Sheila Annie Peters.
|
| 264 |
|
1 |
|a Hoboken, N.J. :
|b Wiley,
|c [2011]
|
| 264 |
|
4 |
|c ©2011
|
| 300 |
|
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|a 1 online resource (pages)
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 347 |
|
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|a data file
|2 rda
|
| 380 |
|
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|a Bibliography
|
| 504 |
|
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|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.
|
| 588 |
0 |
|
|a Print version record.
|
| 520 |
|
|
|a The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceuticascience physiologicallyly-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides the information researchers need to learn these new techniques, its applications are severely limited. Describing the principles, methods, and applications of PBPK modeling as used in pharmaceutics, Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations fills this void.
|
| 650 |
|
0 |
|a Pharmacokinetics
|x Mathematical models.
|
| 650 |
|
0 |
|a Drugs
|x Design
|x Mathematical models.
|
| 650 |
|
2 |
|a Pharmacokinetics.
|
| 650 |
|
2 |
|a Drug Design.
|
| 650 |
|
2 |
|a Models, Biological.
|
| 650 |
|
4 |
|a Drug Design.
|
| 650 |
|
4 |
|a Models, Biological.
|
| 650 |
|
4 |
|a Pharmacokinetics.
|
| 650 |
|
4 |
|a Medicine.
|
| 650 |
|
4 |
|a Pharmacy.
|
| 650 |
|
7 |
|a MEDICAL
|x Pharmacology.
|2 bisacsh
|
| 655 |
|
4 |
|a Electronic books.
|
| 655 |
|
7 |
|a Electronic books.
|2 local
|
| 776 |
0 |
8 |
|i Print version:
|z 9786613618467
|w (DLC) 2011019939
|
| 856 |
4 |
0 |
|u https://doi.org/10.1002/9781118140291
|z Full Text via HEAL-Link
|
| 994 |
|
|
|a 92
|b DG1
|
