Resolving erroneous reports in toxicology and therapeutic drug monitoring : a comprehensive guide /

• Κύριος συγγραφέας: Dasgupta, Amitava, 1958-
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken : John Wiley & Sons, 2012.
• Θέματα: Drug monitoring.; Drugs > Toxicity testing.; Medicine.; Pharmacy.; MEDICAL > Pharmacology.; Electronic books.

The tools for detecting false positives, false negatives, and interference in interactions when testing and monitoring therapeutic drug useFor physicians monitoring a patient's progress, efficacy of treatment is often linked to a patient's response to medication. Determining whether a pati...

Πίνακας περιεχομένων:

• Chapter 1 An Introduction to Tests Performed in Toxicology Laboratories; 1.1. INTRODUCTION; 1.2. ACETAMINOPHEN AND SALICYLATE ASSAYS; 1.3. ANALYSIS OF ALCOHOL; 1.4. THERAPEUTIC DRUG MONITORING; 1.5. ANALYTICAL METHODS USED FOR THERAPEUTIC DRUG MONITORING; 1.6. TESTING OF DRUGS OF ABUSE; 1.7. METHODS USED FOR TESTING OF DRUGS OF ABUSE; 1.8. CONCLUSIONS; Chapter 2 Challenges in Drugs of Abuse Testing; 2.1. INTRODUCTION; 2.2. WORKPLACE DRUG TESTING; 2.3. CHALLENGES OF MEDICAL VERSUS WORKPLACE DRUG TESTING; 2.4. CUT-OFF CONCENTRATIONS.
• 2.5. DRUGS NOT DETECTED IN DRUGS OF ABUSE TESTING PANELS2.6. ADULTERATION OF SPECIMENS AND NEGATIVE DRUGS OF ABUSE SCREEN; 2.7. DRUG TESTING IN ALTERNATIVE SPECIMENS; 2.8. CONCLUSIONS; Chapter 3 False-Positive Results Using Immunoassays for Drugs of Abuse Testing; 3.1. INTRODUCTION; 3.2. INTERFERENCES IN AMPHETAMINE IMMUNOASSAY; 3.3. INTERFERENCES WITH OPIATE IMMUNOASSAY; 3.4. FALSE-POSITIVE TEST RESULTS IN OTHER DRUGS OF ABUSE IMMUNOASSAYS; 3.5. CONCLUSIONS; Chapter 4 True-Positive Drugs of Abuse Test Results Due to Use of Prescriptions and Nonprescription Drugs; 4.1. INTRODUCTION.
• 4.2. POSITIVE AMPHETAMINE/METHAMPHETAMINE TEST RESULT4.3. TRUE-POSITIVE MARIJUANA RESULT; 4.4. TRUE-POSITIVE OPIATE TESTS DUE TO USE OF MEDICATIONS AND INGESTION OF PRODUCTS CONTAINING POPPY SEEDS; 4.5. TRUE-POSITIVE BENZODIAZEPINE TEST RESULTS; 4.6. VARIOUS FACTORS THAT PRODUCE A POSITIVE COCAINE RESULT; 4.7. CONCLUSIONS; Chapter 5 When Toxicology Report Is Negative in a Suspected Overdosed Patient: The World of Designer Drugs; 5.1. INTRODUCTION; 5.2. AMPHETAMINE-TYPE DESIGNER DRUGS; 5.3. OPIOID DESIGNER DRUG; 5.4. PHENCYCLIDINE ANALOGS AS DESIGNER DRUGS; 5.5. GHB AND ITS ANALOGS.
• 5.6. MARIJUANA ANALOGS AS DESIGNER DRUGS5.7. CONCLUSIONS; Chapter 6 Abuse of Magic Mushrooms, Peyote Cactus, Khat, and Solvents: No Readily Available Laboratory Tests; 6.1. INTRODUCTION; 6.2. MAGIC MUSHROOM ABUSE; 6.3. PEYOTE CACTUS: USE AND ABUSE; 6.4. ABUSE OF KHAT AND RELATED COMPOUNDS; 6.5. SOLVENT AND GLUE ABUSE; 6.6. CONCLUSIONS; Chapter 7 Limitations of Blood Alcohol Measurements Using Automated Analyzers and Breath Analyzers; 7.1. INTRODUCTION; 7.2. ALCOHOL METABOLISM; 7.3. MODERATE DRINKING VERSUS ALCOHOL ABUSE; 7.4. BLOOD ALCOHOL DETERMINATION.
• 7.5. BREATH ALCOHOL VERSUS BLOOD ALCOHOL DETERMINATION7.6. BLOOD ALCOHOL DETERMINATION; 7.7. CONCLUSIONS; Chapter 8 Role of the Laboratory in Detecting Other Poisoning, Including Pesticides, Ethylene Glycol, and Methanol; 8.1. INTRODUCTION; 8.2. PESTICIDE POISONING; 8.3. ORGANOPHOSPHATE AND CARBAMATE POISONING: MECHANISM OF POISONING AND SYMPTOMS; 8.4. CHALLENGES IN USING CHOLINESTERASE AS A DIAGNOSTIC TEST FOR ORGANOPHOSPHATE AND CARBAMATE POISONING; 8.5. METHANOL USE AND METHANOL POISONING; 8.6. ETHYLENE GLYCOL USE AND ETHYLENE GLYCOL POISONING; 8.7. CONCLUSIONS.