Parasitic helminths : targets, screens, drugs and vaccines /
| Άλλοι συγγραφείς: | |
|---|---|
| Μορφή: | Ηλ. βιβλίο |
| Γλώσσα: | English |
| Έκδοση: |
Weinheim, Germany :
Wiley-VCH,
2012.
|
| Σειρά: | Drug discovery in infectious diseases ;
v. 3. |
| Θέματα: | |
| Διαθέσιμο Online: | Full Text via HEAL-Link |
Πίνακας περιεχομένων:
- Part one: targets
- Ligand-gated ion channels as targets for anthelmintic drugs: past, current, and future perspectives
- How relevant is Caenorhabditis elegans as a model for the analysis of parasitic nematode biology?
- Integrating and mining helminth genomes to discover and prioritize novel therapeutic targets
- Recent progress in transcriptomics of key gastrointestinal nematodes of animals: fundamental research toward new intervention strategies
- Harnessing genomic technologies to explore the molecular biology of liver flukes-major implications for fundamental and applied research
- RNA interference: a potential discovery tool for therapeutic targets of parasitic nematodes
- RNA interference as a tool for drug discovery in parasitic flatworms
- Part two: screens
- Mechanism-based screening strategies for anthelmintic discovery
- Identification and profiling of nematicidal compounds in veterinary parasitology
- Quantitative high-content screening-based drug discovery against helmintic diseases
- Use of rodent models in the discovery of novel anthelmintics
- To kill a mocking worm: strategies to improve Caenorhabditis elegans as a model system for use in anthelmintic discovery
- Part three: drugs
- Anthelmintic drugs: tools and shortcuts for the long road from discovery to product
- Antinematodal drugs: modes of action and resistance: and worms will not come to thee (Shakespeare: Cymbeline: iv, ii)
- Drugs and targets to perturb the symbiosis of Wolbachia and filarial nematodes
- Promise of Bacillus thuringiensis crystal proteins as anthelmintics
- Monepantel: from discovery to mode of action
- Discovery, mode of action, and commercialization of derquantel
- Praziquantel: too good to be replaced?
- Drug discovery for trematodiases: challenges and progress
- Part four: vaccines
- Barefoot thru' the valley of darkness: preclinical development of a human hookworm vaccine
- Vaccines linked to chemotherapy: a new approach to control helminth infections
- Antifilarial vaccine development: present and future approaches
- Proteases as vaccines against gastrointestinal nematode parasites of sheep and cattle
- Schistosomiasis vaccines: new approaches to antigen discovery and promising new candidates
- Sm14 Schistosoma mansoni fatty acid-binding protein: molecular basis for an antihelminth vaccine
- Mechanisms of immune modulation by Fasciola hepatica: importance for vaccine development and for novel immunotherapeutics
- Prospects for immunoprophylaxis against Fasciola hepatica (liver fluke)
- Vaccines against cestode parasites.
