Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds /
Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, an...
Κύριος συγγραφέας: | |
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Μορφή: | Ηλ. βιβλίο |
Γλώσσα: | English |
Έκδοση: |
Weinheim :
Wiley-VCH Verlag GmBH & Co.,
[2012]
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Θέματα: | |
Διαθέσιμο Online: | Full Text via HEAL-Link |
Περίληψη: | Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy. |
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Φυσική περιγραφή: | 1 online resource (xvi, 605 pages) : illustrations |
Βιβλιογραφία: | Includes bibliographical references and index. |
ISBN: | 9783527645640 3527645640 9783527645664 3527645667 |
DOI: | 10.1002/9783527645640 |