Lead optimization for medicinal chemists : pharmacokinetic properties of functional groups and organic compounds /

Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, an...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριος συγγραφέας: Dörwald, Florencio Zaragoza
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: Weinheim : Wiley-VCH Verlag GmBH & Co., [2012]
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
LEADER 03319nam a2200733 4500
001 ocn805654697
003 OCoLC
005 20170124070457.9
006 m o d
007 cr |||||||||||
008 120809t20122012gw a ob 001 0 eng d
040 |a YDXCP  |b eng  |e rda  |e pn  |c YDXCP  |d E7B  |d OCLCQ  |d COO  |d OCLCO  |d DG1  |d EBLCP  |d N$T  |d MHW  |d CCO  |d IDEBK  |d OCLCF  |d IUL  |d OCLCQ  |d D6H  |d AZK  |d LOA  |d GrThAP 
019 |a 961515877  |a 962633579  |a 966211547 
020 |a 9783527645640 
020 |a 3527645640 
020 |a 9783527645664 
020 |a 3527645667 
020 |z 9783527332267 
020 |z 352733226X 
020 |z 9783527645657 
020 |z 3527645659 
020 |z 9783527645671 
020 |z 3527645675 
020 |z 9781283893244 
020 |z 128389324X 
029 1 |a AU@  |b 000050590692 
029 1 |a AU@  |b 000053019049 
029 1 |a NZ1  |b 14976578 
029 1 |a NLGGC  |b 356818578 
029 1 |a DKDLA  |b 820120-katalog:000599880 
029 1 |a GBVCP  |b 790199491 
029 1 |a DEBBG  |b BV043394967 
035 |a (OCoLC)805654697  |z (OCoLC)961515877  |z (OCoLC)962633579  |z (OCoLC)966211547 
050 4 |a RS403 
072 7 |a MED  |x 023000  |2 bisacsh 
072 7 |a MED  |x 058170  |2 bisacsh 
072 7 |a MED  |x 071000  |2 bisacsh 
072 7 |a MED  |x 072000  |2 bisacsh 
082 0 4 |a 615.19 
049 |a MAIN 
100 1 |a Dörwald, Florencio Zaragoza. 
245 1 0 |a Lead optimization for medicinal chemists :  |b pharmacokinetic properties of functional groups and organic compounds /  |c Florencioa Zaragoza Dörwald. 
264 1 |a Weinheim :  |b Wiley-VCH Verlag GmBH & Co.,  |c [2012] 
264 4 |c ©2012 
300 |a 1 online resource (xvi, 605 pages) :  |b illustrations 
336 |a text  |b txt  |2 rdacontent 
337 |a computer  |b c  |2 rdamedia 
338 |a online resource  |b cr  |2 rdacarrier 
380 |a Bibliography 
588 0 |a Online resource; title from home page (viewed May 23, 2014). 
504 |a Includes bibliographical references and index. 
520 |a Small structural modifications can significantly affect the pharmacokinetic properties of drug candidates. This book, written by a medicinal chemist for medicinal chemists, is a comprehensive guide to the pharmacokinetic impact of functional groups, the pharmacokinetic optimization of drug leads, and an exhaustive collection of pharmacokinetic data, arranged according to the structure of the drug, not its target or indication. The historical origins of most drug classes and general aspects of modern drug discovery and development are also discussed. The index contains all the drug names and sy. 
505 0 |a pt. 1. Introduction -- pt. 2. The pharmacokinetic properties of compound classes. 
650 0 |a Pharmaceutical chemistry. 
650 7 |a MEDICAL  |x Drug Guides.  |2 bisacsh 
650 7 |a MEDICAL  |x Nursing  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacology.  |2 bisacsh 
650 7 |a MEDICAL  |x Pharmacy.  |2 bisacsh 
650 7 |a Pharmaceutical chemistry.  |2 fast  |0 (OCoLC)fst01060115 
655 4 |a Electronic books. 
655 7 |a Electronic books.  |2 local 
776 0 8 |i Print version:  |a Dörwald, Florencio Zaragoza.  |t Lead optimization for medicinal chemists.  |d Weinheim : Wiley-VCH, ©2012  |z 9783527332267  |w (OCoLC)793414338 
856 4 0 |u https://doi.org/10.1002/9783527645640  |z Full Text via HEAL-Link 
994 |a 92  |b DG1