Metal transporters /

• Άλλοι συγγραφείς: Lutsenko, Svetlana, Arguello, Jose M.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: San Diego : Elsevier Science, 2012.
• Σειρά: Current topics in membranes ; 69.
• Θέματα: Membrane, Basement.; Membranes (Biology); Metals > Speciation.; SCIENCE > Life Sciences > Cell Biology.; Electronic books.

 This volume of Current Topics in Membranes focuses on metal transmembrane transporters and pumps, a recently discovered family of membrane proteins with many important roles in the physiology of living organisms. The book summarizes the most recent advances in the field of metal ion transport and provides a broad overview of the major classes of transporters involved in homeostasis of heavy metals. Various families of the transporters and metal specificities are discussed with the focus on the structural and mechanistic aspects of their function and regulation. The reader will access information obtained through a variety of approaches ranging from X-ray crystallography to cell biology and bioinformatics, which have been applied to transporters identified in diverse biological systems, such as pathogenic bacteria, plants, humans and others. 

 Transferrin-Mediated Cellular Iron Delivery -- Structure, Function and Binding Selectivity and Stereoselectivity of Siderophore- ron Outer Membrane Transporters -- Iron Transport Machinery of Human Cells: Players and Their Interactions -- Structure and Function of Copper Uptake Transporters -- Toward a Molecular Understanding of Metal Transport by P1B-Type ATPases -- Regulation of Copper Transporters in Human Cells -- Metal Export by CusCFBA, the Periplasmic Cu(I)/Ag(I) Transport System of Escherichia coli -- Molecular Architecture and Function of ZnT Transporters -- The Cation Selectivity of the ZIP Transporters -- Nramp: from Sequence to Structure and Mechanism of Divalent Metal Import -- Genetic and Biochemical Approaches for Studying the Yellow Stripe-Like Transporter Family in Plants -- Pathways of Arsenic Uptake and Efflux -- Extracellular Heme Uptake and the Challenges of Bacterial Cell Membranes -- The Mechanisms of Mg2+ and Co2+ Transport by the CorA Family of Divalent Cation Transporters.