Mass spectrometry for drug discovery and drug development /

• Άλλοι συγγραφείς: Korfmacher, Walter A.
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : Wiley, 2013.
• Σειρά: Wiley-Interscience series on mass spectrometry.
• Θέματα: Drugs > Analysis.; Drug development.; Mass spectrometry.; Drug Discovery.; Mass Spectrometry > methods.; Peptides > analysis.; Pharmaceutical Preparations > analysis.; Proteins > analysis.; Drug discovery.; Mass spectrometry > Methods.; Peptides > Analysis.; Pharmaceutical preparations > Analysis.; Proteins > Analysis.; MEDICAL > Drug Guides.; MEDICAL > Nursing > Pharmacology.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; Electronic books.
• Φυσική περιγραφή: 1 online resource (xii, 461 pages, [16] pages of plates)) : illustrations (some color).
• Βιβλιογραφία: Includes bibliographical references and index.
• ISBN: 9781118516157; 111851615X; 9781118516126; 1118516125; 9781283917520; 1283917521
• DOI: 10.1002/9781118516157

This book presents a summary of the ways mass spectrometry is used in various stages of drug discovery and development including early support of medicinal chemistry, drug metabolism studies, distribution, degradation, and various development assays. The book includes a balance of basic and advanced information. Specific chapters relate to various stages in the process (e.g., discovery) as well as chapters on topics of current interest (lipidomics and SiRNA) are covered.