Success probability estimation with applications to clinical trials

• Main Author: De Martini, Daniele, 1965-
• Format: Electronic eBook
• Language: English
• Published: Hoboken, N.J. : Wiley, [2013]
• Subjects: Clinical trials > Statistical methods.; Probabilities.; Statistics.; Clinical Trials as Topic.; Probability.; Pharmaceutical Preparations.; Statistics as Topic.; MEDICAL > Laboratory Medicine.; Clinical trials / Statistical methods.; Electronic books.

Provides an introduction to the various statistical techniques involved in medical research and drug development with a focus on estimating the success probability of an experiment Success Probability Estimation with Applications to Clinical Trials details the use of success probability estimation i...

Table of Contents:

• Basic statistical tools
• Reproducibility probability estimation
• Sample size estimation
• Robustness and corrections in sample size estimation
• General parametric SP estimation
• SP estimation for student's t statistical tests
• SP estimation for Gaussian distributed test statistics
• SP estimation for Chisquare statistical tests
• General nonparametric SP estimation with applications to the Wilcoxon test.