Methods in protein design. Volume 523 /

Λεπτομέρειες βιβλιογραφικής εγγραφής
Άλλοι συγγραφείς: Keating, Amy E.
Μορφή: Ηλ. βιβλίο
Γλώσσα:English
Έκδοση: San Diego, Calif. : Academic, 2013.
Σειρά:Methods in enzymology ; volume 523.
Θέματα:
Διαθέσιμο Online:Full Text via HEAL-Link
Πίνακας περιεχομένων:
  • Computational design of novel protein binders and experimental affinity maturation
  • Mining tertiary structural motifs for assessment of designability
  • Computational methods for controlling binding specificity
  • Flexible backbone sampling methods to model and design protein alternative conformations
  • Osprey: protein design with ensembles, flexibility, and provable algorithms
  • Scientific benchmarks for guiding macromolecular energy function improvement
  • Molecular dynamics simulations for the ranking, evaluation, and refinement of computationally designed proteins
  • Multistate protein design using CLEVER and CLASSY
  • Using analyses of amino acid coevolution to understand protein structure and function
  • Evolution-based design of proteins
  • Protein engineering and stabilization from sequence statistics: variation and covariation analysis
  • Enzyme engineering by targeted libraries
  • Generation of high-performance binding proteins for pepetide motifs by affinity clamping
  • Engineering fibronectin-based binding proteins by yeast surface display
  • Engineering and analysis of peptide-recognition domain specificities by phage display and deep sequencing
  • Efficient sampling of SCHEMA chimera families to identify useful sequence elements
  • Protein switch engineering by domain insertion
  • Design of chimeric proteins by combination of subdomain-sized fragments
  • [alpha]-helix mimicry with [alpha/beta]-peptides.