Protein-protein interactions in drug discovery /

Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of prote...

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Bibliographic Details
Other Authors: Dömling, Alexander
Format: eBook
Language:English
Published: Weinheim : Wiley-VCH, 2013.
Series:Methods and principles in medicinal chemistry ; v. 56.
Subjects:
Online Access:Full Text via HEAL-Link
Description
Summary:Treating protein-protein interactions as a novel and highly promising class of drug targets, this volume introduces the underlying strategies step by step, from the biology of PPIs to biophysical and computational methods for their investigation. The main part of the book describes examples of protein targets for which small molecule modulators have been developed, covering such diverse fields as cancer, autoimmune disorders and infectious diseases. Tailor-made for the practicing medicinal chemist, this ready reference includes a wide selection of case studies taken straight from the devel.
Physical Description:1 online resource (xxi, 314 pages) : illustrations.
Bibliography:Includes bibliographical references and index.
ISBN:9783527648238
3527648232
9783527648207
3527648208
DOI:10.1002/9783527648207