High-throughput screening methods in toxicity testing /

• Other Authors: Steinberg, Pablo (Editor)
• Format: eBook
• Language: English
• Published: Hoboken, New Jersey : John Wiley & Sons Inc., [2013]
• Subjects: High throughput screening (Drug development); Toxicity testing.; SCIENCE > Chemistry > Industrial & Technical.; MEDICAL > Drug Guides.; MEDICAL > Nursing > Pharmacology.; MEDICAL > Pharmacology.; MEDICAL > Pharmacy.; Electronic books.

"High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply...

Table of Contents:

• pt. 1. General aspects
• pt. 2. High-throughput assays to assess different cytotoxicity endpoints
• pt. 3. High-throughput assays to assess DNA damage and carcinogenesis
• pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity
• pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.