Equilibria and kinetics of biological macromolecules

• Main Author: Hermans, Jan
• Other Authors: Lentz, Barry
• Format: Electronic eBook
• Language: English
• Published: Hoboken, N.J. : John Wiley & Sons, [2014]
• Subjects: Biomedical materials.; Macromolecules.; MEDICAL > Pharmacology.; Biocompatible Materials > pharmacokinetics.; Biophysical Phenomena.; Macromolecular Substances > pharmacokinetics.; Molecular Conformation.; Electronic books.

Table of Contents:

• Thermodynamics
• Four basic quantum mechanical models of nuclear & electronic motion : a synopsis
• Molecular structure and interactions
• Water and the hydrophobic effect
• The molecular partition function
• System ensembles and partition functions
• Sampling molecular systems with simulations
• Binding equilibria
• Thermodynamics of molecular interactions
• Elements of statistical mechanics of liquids and solutions
• Analysis of binding equilibria in terms of partition functions
• Coupled equilibria
• Allosteric function
• Charged groups : binding of hydrogen ions, solvation and charge-charge interactions
• Some elements of polymer physics
• Helix-coil equilibria
• Protein unfolding equilibria
• Elasticity of biological materials
• Kinetics
• Kinetics of protein folding
• Irreversible and stochastic processes.