Trypanosomatid diseases : molecular routes to drug discovery /

• Άλλοι συγγραφείς: Jäger, Timo, Koch, Oliver, Flohé, L. (Leopold), 1938-
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Weinheim : Wiley-VCH, 2013.
• Έκδοση: First edition.
• Σειρά: Drug discovery in infectious diseases ; v. 4.
• Θέματα: Parasitic diseases.; Trypanosomatidae.; MEDICAL > Parasitology.; Trypanosomiasis > Chemotherapy.; Trypanosomiasis.; Electronic books.

This is the first resource to provide researchers in academia and industry with an urgently needed update summarizing the current knowledge and possibilities for drug intervention against Trypanosomatides all in one volume. As such, it covers every aspect of the topic from basic research findings, v...

Πίνακας περιεχομένων:

• pt. 1. Disease burden, current treatments, medical needs, and strategic approaches
• pt. 2. Metabolic peculiarities in the trypanosomatid family guiding drug discovery
• pt. 3. Validation and selection of drug targets in kinetoplasts
• pt. 4. Examples of target-based approaches and compounds under consideration.