Trypanosomatid diseases : molecular routes to drug discovery /

• Other Authors: Jäger, Timo, Koch, Oliver, Flohé, L. (Leopold), 1938-
• Format: eBook
• Language: English
• Published: Weinheim : Wiley-VCH, 2013.
• Edition: First edition.
• Series: Drug discovery in infectious diseases ; v. 4.
• Subjects: Parasitic diseases.; Trypanosomatidae.; MEDICAL > Parasitology.; Trypanosomiasis > Chemotherapy.; Trypanosomiasis.; Electronic books.

This is the first resource to provide researchers in academia and industry with an urgently needed update summarizing the current knowledge and possibilities for drug intervention against Trypanosomatides all in one volume. As such, it covers every aspect of the topic from basic research findings, v...

Table of Contents:

• pt. 1. Disease burden, current treatments, medical needs, and strategic approaches
• pt. 2. Metabolic peculiarities in the trypanosomatid family guiding drug discovery
• pt. 3. Validation and selection of drug targets in kinetoplasts
• pt. 4. Examples of target-based approaches and compounds under consideration.