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04676nam a2200817 4500 |
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ocn841187101 |
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OCoLC |
| 005 |
20170124071451.9 |
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m o d |
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cr ||||||||||| |
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130418s2014 nju ob 001 0 eng |
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|a 2013016032
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|2 23
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| 084 |
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|a SCI010000
|2 bisacsh
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| 049 |
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|a MAIN
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| 100 |
1 |
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|a McCarthy, J. R.
|
| 245 |
1 |
0 |
|a Enzyme technologies :
|b pluripotent players in discovering therapeutic agents /
|c J.R. McCarthy, Hsiu-Chiung Yang, Wu-Kuang Yeh.
|
| 264 |
|
1 |
|a Hoboken, New Jersey :
|b Wiley-Interscience,
|c [2014]
|
| 300 |
|
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|a 1 online resource.
|
| 336 |
|
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|a text
|b txt
|2 rdacontent
|
| 337 |
|
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|a computer
|b c
|2 rdamedia
|
| 338 |
|
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|a online resource
|b cr
|2 rdacarrier
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| 490 |
1 |
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|a Chemical Biology of Enzymes for Biotechnology and Pharmaceutical Applications ;
|v Volume II
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| 504 |
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|a Includes bibliographical references and index.
|
| 520 |
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|a "This book highlights how, what, and where enzymes have become critical in pharmaceutical and biotechnology research. It provides in-depth reviews of recent developments in select topics on biosynthesis, biocatalysis, and chemical biology of enzymes. Broad coverage of enzymatic assays includes emerging assay technologies for key enzyme classes in pharmaceutical research. In addition to new developments in proteomics, this book includes two emerging technologies in Life Sciences: metabolomics (including glycomics and lipidomics) and preclinomics. This volume reviews important progress on the chemical biology of enzymes in the post-genomic era"--
|c Provided by publisher.
|
| 588 |
0 |
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|a Print version record and CIP data provided by publisher.
|
| 505 |
0 |
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|a Machine generated contents note: pt. A ENZYMES -- ESSENTIAL WORKHORSES IN PHARMACEUTICAL RESEARCH -- 1. Assay Technologies for Proteases / Rathnam Chaguturu -- 2. Discovery and Development of Isozyme-Selective Inhibitors Involved in Lipid Metabolism / Hiroshi Tomoda -- 3. Covalent Enzyme Inhibition in Drug Discovery and Development / Shujaath Mehdi -- 4. Preclinomics: Enzyme Assays and Rodent Models for Metabolic diseases / Richard G. Peterson -- pt. B ENZYMES -- INDISPENSABLE TOOLS FOR IMPROVING DRUGGABILITY -- 5. Enzymes and Targeted Activation of Prodrugs / Longqin Hu -- 6. Evolution of an Orally Active Prodrug of Gemcitabine / James R. McCarthy -- 7. Enzymatically Activated Phosphate and Phosphonate Prodrugs / Charles E. McKenna -- pt. C ENZYMES -- POWERFUL WEAPONS FOR CORRECTING NATURE'S ERRORS -- 8. Treatment Options for Mucopolysaccharidosis Type II (Hunter's Syndrome) / Michael Beck -- 9. Enzyme Replacement Therapy for Fabry Disease / Ozlem Goker-Alpan -- 10. Methods and Principles of Pancreatic Function Tests / Peter Layer.
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| 650 |
|
0 |
|a Enzyme inhibitors.
|
| 650 |
|
0 |
|a Enzymes
|x Pharmacokinetics.
|
| 650 |
|
0 |
|a Drugs
|x Design.
|
| 650 |
1 |
2 |
|a Enzyme inhibitors.
|
| 650 |
1 |
2 |
|a Enzymes
|x pharmacokinetics.
|
| 650 |
2 |
2 |
|a Drug Design.
|
| 650 |
|
7 |
|a SCIENCE
|x Biotechnology.
|2 bisacsh
|
| 655 |
|
4 |
|a Electronic books.
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| 655 |
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0 |
|a Electronic books.
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| 700 |
1 |
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|a Yang, Hsiu-Chiung.
|
| 700 |
1 |
|
|a Yeh, Wu-Kuang,
|d 1942-
|
| 776 |
0 |
8 |
|i Print version:
|a McCarthy, J.R.
|t Design of enzyme inhibitors.
|d Hoboken, New Jersey : Wiley-Interscience, [2014]
|z 9780470286265
|w (DLC) 2013013968
|
| 830 |
|
0 |
|a Chemical biology of enzymes for biotechnology and pharmaceutical applications ;
|v v. 2.
|
| 856 |
4 |
0 |
|u https://doi.org/10.1002/9781118739907
|z Full Text via HEAL-Link
|
| 994 |
|
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|a 92
|b DG1
|
