Stem cell therapeutics for cancer /

• Άλλοι συγγραφείς: Shah, Khalid (Επιμελητής έκδοσης)
• Μορφή: Ηλ. βιβλίο
• Γλώσσα: English
• Έκδοση: Hoboken, N.J. : Wiley Blackwell, [2013]
• Έκδοση: First edition.
• Θέματα: Tumors.; Mesenchymal stem cells.; Stem cells.; Neoplasms > therapy.; Stem Cells > physiology.; Mesenchymal Stromal Cells > physiology.; Mesenchymal Stem Cell Transplantation > methods.; Mesenchymal stem cell transplantation > Methods.; Mesenchymal stromal cells > Physiology.; Neoplasms > Therapy.; Stem cells > Physiology.; HEALTH & FITNESS > Diseases > General.; MEDICAL > Clinical Medicine.; MEDICAL > Diseases.; MEDICAL > Evidence-Based Medicine.; MEDICAL > Internal Medicine.; Electronic books.

 "Stem Cell Therapeutics for Cancer covers the application of stem cells in various cancers, with an emphasis on the aspects of these strategies that are critical to the success of future stem cell-based therapies for cancer. Topics covered in the book include stem cell sources, tumor specificity, targeted therapeutics, visualizing the stem cell, and therapeutic agent pharmacokinetics. Each chapter contains a brief introduction to the cancer, followed by an exploration of how engineered stem cells have been utilized to cure the disease in mouse models and in early phase clinical trials"--Publisher's description. 

 Section 1: Introduction. Stem cell sources and their potential for cancer therapeutics / Khalid Shah -- Section 2: Migration and fate of stem cells. The role of CXCR4 as a mediator of glioma-tropic neural precursor cell migration / Moneeb Ehtesham, Elliot Min, and Rebecca Kasl -- Tumor tropism of mesenchymal stem cells / Paula Y. P. Lam and Ivy A.W. Ho -- Section 3: Stem cell therapy in brain cancer. Stem cell-mediated TRAIL therapy for highly aggressive brain tumors / Khalid Shah -- Stem cell-mediated prodrug gene therapy of high-grade brain tumors / Cestmir Altaner -- Role of naïve cord blood stem cells in glioma therapy / Venkata Ramesh Dasari, Kiran Kumar Velpula, and Jasti S. Rao -- Stem cell-based antiangiogenic therapies for brain tumors / Navid Redjal and Khalid Shah -- Treatment of metastatic neuroblastoma with mesenchymal stem cell-based oncolytic virotherapy / Manuel Ramírez and Javier García-Castro -- Section 4: Stem cell therapy in other cancer types. Umbilical cord matrix stem cells for cytotherapy of breast cancer / Naomi Ohta, Atsushi Kawabata, Deepthi Uppalapati, Susumu Ishiguro, Deryl Troyer, and Masaaki Tamura -- Mesenchymal stromal cells as effective tumor antigen-presenting cells in cancer therapeutics / Raphaëlle Romieu-Mourez and Jacques Galipeau -- Diagnostic and therapeutic mesenchymal stem cells for breast cancer treatment / Róisín Dwyer -- Genetically engineered stem cell therapies targeting gastrointestinal malignancy / Emily Keung, Peter J. Nelson, and Claudius Conrad -- Mesenchymal stem cells in prostate cancer: clinical opportunities / Diptiman Chanda and Selvarangan Ponnazhagan -- Primed mesenchymal stromal cells for cancer therapy / Augusto Pessina, Arianna Bonomi, Eugenio Parati, Roberto Pallini, and Giulio Alessandri -- Section 5: Combinatorial stem cell therapies. MicroRNA adjuvants in stem cell-based cancer therapy / Maarten C. J. Anderegg and Maarten F. Corsten -- Stem cell-based combination therapies for cancer: systemic delivery of a PI K/mTOR inhibitor (PI-103) and stem cell-mediated delivery of TRAIL in brain tumors / Tugba Bagci-Onder -- The efficacy of clinically approved agents with stem cell-delivered therapeutics for cancer therapy / Hiroaki Wakimoto and Khalid Shah -- Section 6: Tracking stem cells and stem cell-based therapeutics. Imaging migration and fate of stem cells in experimental models of cancer / Deepak Bhere and Khalid Shah -- Multifunctional molecules for interrogating stem cell-based therapeutics / Shawn Hingtgen -- Tracking cancer-targeted MSC with PET imaging / Véronique Roelants and Jean-Louis Vanoverschelde.